Eric R. Gamazon, PhD, MS is a tenured member of the faculty of the Division of Genetic Medicine at Vanderbilt University Medical Center. He is a Life Member of Clare Hall, University of Cambridge.
He is interested in what can be learned from DNA sequence and multi-omics data about disease mechanism, therapeutic intervention, molecular evolution, and genome function. An ongoing project involves understanding the effect of genetic variation on gene regulation across tissues and cell types to gain insights into disease mechanisms and therapeutic targets. He utilizes large-scale DNA biobank data linked to electronic health records, along with data science and computation, to identify genes involved in human health and disease in diverse populations, to discover novel biomarkers, and to enable a comprehensive systems view of the disease phenome.
His laboratory is an interdisciplinary group with expertise in computational genomics and molecular biology. The lab has been the research training ground for a Barry Goldwater Scholar, a Fulbright Scholar, and a NARSAD Young Investigator Grant recipient. See https://my.vanderbilt.edu/ericgamazon/ for more information.
He co-chaired the GWAS Working Group of the GTEx Consortium and has served on various National Institutes of Health (NIH) study sections. He was a recipient (2019) of the inaugural Genomic Innovator Award from the NIH.
Dr. Bastarache is a physician-scientist with a mechanistic and translational research program in acute and chronic lung diseases including acute respiratory distress syndrome (ARDS) and bronchiectasis. She also has an interest in non-pulmonary organ dysfunction during sepsis and studies delirium and acute kidney injury in experimental models. Her diverse research approach uses a combination of cell, mouse and human models of lung injury and repair to define the fundamental cellular and molecular mechanisms that regulate organ injury including ARDS, delirium and acute kidney injury as well large clinical and genetic datasets to generate insights into individual variability in risk and outcomes from ARDS. She also has an interest in leveraging the EMR and novel phenotyping methods to identify and study subjects with underlying genetic causes of chronic lung diseases such as bronchiectasis with the goal of developing tools to help clinicians achieve a timely and accurate diagnosis.
Lab website: www.lstci.org
Twitter: @JulesBass6
