Manus Donahue, PhD


(615) 322-8350

Dr. Manus Donahue is an Associate Professor of Radiology and Radiological Sciences with a secondary appointment in the Department of Neurology. Dr. Donahue works in the Vanderbilt University Institute of Imaging Science where his work focuses on development and application of new methods for studying brain function in health and disease. These methods are sensitive to physiological parameters such as cerebral blood flow, cerebral blood volume, pH, oxygen extraction fraction and the cerebral metabolic rate of oxygen, parameters that may adjust prior to symptom expression and irreversible tissue damage in many diseases.

Since 2012, Dr. Donahue has collaborated with Dr. Jefferson and her colleagues on the Memory & Aging Project and the Alzheimer’s Disease Neuroimaging Initiative dataset to understand how vascular integrity affects the pathogenesis and clinical manifestation of Alzheimer’s disease.