Jill H. Simmons, M.D.

Associate Professor
Pediatrics/Monroe Carell Jr. Children’s Hospital
Office Address
Doctors Office Tower
2200 Children's Way
Room / Suite
(615) 322-7427

Dr. Jill Simmons is an Associate Professor of Pediatrics in the Ian M Burr Division of Pediatric Endocrinology and Diabetes at Vanderbilt University Medical Center. She is the founder and director of the Vanderbilt Program for Pediatric Metabolic Bone Disease, the founder and chair of the Hazinski Society for Faculty Development, and the Director for Faculty Mentorship Programs at Vanderbilt University. 

Dr. Simmons’ clinical and research interests include pediatric metabolic bone diseases such as hypophosphatasia, osteogenesis imperfecta, osteoporosis, and rickets. She has been a local principal investigator for multiple clinical trials, including asfotase alpha in infants with severe hypophosphatasia, denosumab in pediatric patients with osteogenesis imperfecta, and an FGF23 antagonist in pediatric patients with hypophosphatemic rickets.  She is an active investigator in an international longitudinal observational registry of patients with hypophosphatasia.  She also is a local principal investigator in the Type 1 Diabetes Exchange, a multi-institutional collaboration to improve the lives and care of patients with type 1 diabetes.

Dr. Simmons’ research has been presented at the Scientific Sessions of the American Diabetes Association, and the annual meetings of the Pediatric Academic Societies, the Endocrine Society, and the European Society for Pediatric Endocrinology.  Her work has been published in the New England Journal of Medicine, Journal of Pediatrics, Diabetes Care, Pediatric Blood and Cancer, and Biology of Blood and Marrow Transplatation.  She serves as a regular reviewer for Diabetes Care, Journal of Clinical Endocrinology and Metabolism, Journal of Clinical Investigation, Pediatric Blood and Cancer, and Pediatric Diabetes.

In addition to her research, she is an active clinician and educator.  She spends the majority of her time with patients as well as educating pediatric residents and endocrinology fellows to better care for children with endocrine diseases. She has been named one of America’s Best Doctors by Castle Connelly for the past 4 years.



Research Information


Pediatric Metabolic Bone Diseases

  • Hypophosphatasia

  • ​Osteogenesis imperfects

  • Osteoporosis

  • Rickets

  • ​Endocrine and bone effects of pediatric cancer and its treatment