Guelcher publications

Selected Publications (since 2012)

  1. T Yoshii, JE Dumas, A Okawa, D Spengler, SA Guelcher. Synthesis, characterization of calcium phosphates/polyurethane composites for weight bearing implants. Journal of Biomedical Materials Research Part B: Applied Biomaterials 100(1):32-40, 2012.
  2. JE Dumas, P Brown-Baer, EM Prieto, T Guda, R Hale, JC Wenke, SA Guelcher. Injectable reactive biocomposites for bone healing in critical-size rabbit calvarial defects. Biomedical Materials 7(2): 024112, 2012.
  3. JM Page, EM Prieto, JE Dumas, KJ Zienkiewicz, JC Wenke, P Brown-Baer, SA Guelcher. Reactivity and biocompatibility of injectable polyurethane/allograft bone biocomposites. Acta Biomaterialia, 8:4405–4416, 2012.
  4. CJ Sanchez Jr., EM Prieto, CA Kruger, KJ Zienkiewicz, DR Romano, CL Ward, KS Akers, SA Guelcher, JC Wenke. Effects of Local Delivery of D-Amino Acids from Biofilm-Dispersive Scaffolds on Infection in Contaminated Rat Segmental Defects. Biomaterials 34(30):7533-43, 2013.
  5. JE Dumas, EM Prieto, KJ Zienkiewicz, T Guda, JC Wenke, JM Bible, GE Holt, SA Guelcher. Balancing the rates of new bone formation and polymer degradation enhances healing of weight-bearing allograft/polyurethane composites in rabbit femoral defects. Tissue Engineering Part A 20(1-2):115-29, 2014.
  6. CE Nelson, AJ Kim, A Hanna, EJ Adolph, F Yu, MK Gupta, K Hocking, JM Davidson, SA Guelcher, CL Duvall. Tunable Delivery of siRNA from a Biodegradable Scaffold to Promote Angiogenesis in vivo. Advanced Materials 26(4):607-14, 2014.
  7. JL Martin, MK Gupta, JM Page, F Yu, JM Davidson, SA Guelcher, CL Duvall. Synthesis of a Porous, Biocompatible Tissue Engineering Scaffold Selectively Degraded by Cell-Generated Reactive Oxygen Species. Biomaterials 35(12):3766-76, 2014.
  8. JA Sterling, SA Guelcher. Biomaterial scaffolds for treating osteoporotic bone. Current Osteoporosis Reports 12(1): 48–54, 2014.
  9. T Yoshii, AE Hafeman, GE Gutierrez, GR Mundy, SA Guelcher. Local injection of lovastatin in biodegradable polyurethane scaffolds enhances bone regeneration. Journal of Tissue Engineering and Regenerative Medicine 8(8): 589–595, 2014.
  10. AJ Harmata, CL Ward, KJ Zienkiewicz, JC Wenke, SA Guelcher.  Investigating the Effects of Surface-Initiated Polymerization of ε-Caprolactone to Bioactive Glass Particles on the Mechanical Properties of Settable Polymer/Ceramic Composites. Journal of Materials Research 29: 20, 2014.
  11. RW Johnson, AR Merkel, JM Page, NS Ruppender, SA Guelcher, JA Sterling. Wnt signaling induces gene expression of factors associated with bone destruction in lung and breast cancer.  Clin Exp Metastasis 31(8):945-59, 2014. PMC4258192
  12. R Guo, CL Ward, JM Davidson, CL Duvall, JC Wenke, SA Guelcher. A Transient Cell-Shielding Method for Viable MSC Delivery within Hydrophobic Scaffolds Polymerized In Situ. Biomaterials 54:21-33, 2015. PMC4409667
  13. JM Page, AR Merkel, NS Ruppender, UC Dadwal, S Cannonier, R Guo, S Basu, SA Guelcher, JA Sterling. Matrix rigidity regulates the transition of tumor cells to a bone-destructive phenotype through integrin beta3 and TGF-beta receptor type II. Biomaterials 64:33-44, 2015. PMC4681301
  14. AJ Harmata, S Uppuganti, M Granke, SA Guelcher, JS Nyman. Compressive fatigue and fracture toughness behavior of injectable, settable bone cements Journal of the Mechanical Behavior of Biomedical Materials 51:345-355, 2015.
  15. R Guo, S Lu, JM Page, AR Merkel, S Basu, JA Sterling, and SA Guelcher. Fabrication of 3D Scaffolds with Precisely Controlled Substrate Modulus and Pore Size by Templated-Fused Deposition Modeling to Direct Osteogenic Differentiation. Adv Healthc Mater 4(12):1826-32, 2015. PMC4558627
  16. R Guo, A Merkel, JA Sterling, JM Davidson, SA Guelcher. Substrate Modulus of 3D-Printed Scaffolds Regulates the Regenerative Response in Subcutaneous Implants through the Macrophage Phenotype and Wnt Signaling. Biomaterials 73:85-95, 2015.
  17. EM Prieto, AD Talley, S, Drapeau, K Kalpakci, SA Guelcher. Effects of particle size and demineralized bone matrix on remodeling of settable bone grafts in a rabbit femoral condyle defect model.  Journal of Biomedical Materials Research Part B: Applied Biomaterials 103(8):1641-51, 2015.
  18. AJ Harmata, C Sanchez, JC Wenke, SA Guelcher. D-amino acid inhibits biofilm but not new bone formation in an ovine model. Clinical Orthopedics and Related Research 473(12):3951-61, 2015.
  19. AD Talley, KN Kalpakci, KJ Zienkiewicz, DL Cochran, SA Guelcher. Effects of rhBMP-2 Dose and Ceramic Composition on New Bone Formation and Space Maintenance in a Canine Mandibular Ridge Saddle Defect Model. Tissue Engineering Part A 22(5-6):469-79, 2016.
  20. R Guo, AR Merkel, S Lu, JA Sterling, SA Guelcher. Substrate modulus regulates osteogenic differentiation of rat mesenchymal stem cells through integrin B1 and BMP receptor type IA. J. Mater. Chem. B 4:3584-93, 2016. Invited article for a themed issue on Stem Cells.
  21. EJ Adolph, R Guo, JM Davidson, SA Guelcher, LB Nanney. Injectable, Settable Lysine-derived Polyurethane Scaffolds Delay Wound Contraction and Promote Healing of Full-Thickness Excisional Wounds in Pigs.  Journal of Biomedical Materials Research B: Applied Biomaterials 2015 Sep 7. doi: 10.1002/jbm.b.33515. [Epub ahead of print].
  22. J Vanderburgh, JA Sterling, SA Guelcher. 3D printed biomimetic scaffolds for in vitro models of disease progression and drug screening. Ann Biomed Eng. 2016 May 11. [Epub ahead of print] Invited Review Article.
  23. S Hendrix, TJ Spoonmore, AD Wilde, NE Putnam, ND Hammer, DJ Snyder, SA Guelcher, EP Skaar, JE Cassat. Repurposing the nonsteroidal anti-inflammatory drug diflunisal as an osteoprotective, anti-virulence therapy for Staphylococcus aureus osteomyelitis. Antimicrob Agents Chemother, Jun 20. pii: AAC.00834-16. [Epub ahead of print].
  24. AD Talley, KN Kalpakci, SA Guelcher. Remodeling of injectable, settable bone grafts in a sheep femoral condyle defect model. Journal of Biomedical Materials Research B: Applied Biomaterials. 2016 Aug 10. doi: 10.1002/jbm.b.33767. [Epub ahead of print].