A selection of publications from current department members since 2018:
Risner ML, Pasini S, Chamling X, McGrady NR, Goldberg JL, Zack DJ, Calkins DJ.
Intrinsic Morphologic and Physiologic Development of Human Derived Retinal Ganglion Cells In Vitro.
Transl Vis Sci Technol. 2021 Aug 12;10(10):1.
This study examined the intrinsic morphologic and physiologic development of human retinal ganglion cells. Cells were derived from human pluripotent stem cells and cultured for 7 weeks. The cells continued to mature over this time. The maturation state of the cells should be considered when considering their use as treatments for optic neuropathies.
Baratta RO, Del Buono BJ, Schlumpf E, Ceresa BP, Calkins DJ.
Collagen Mimetic Peptides Promote Corneal Epithelial Cell Regeneration.
Front Pharmacol. 2021 Aug 16;12:705623.
This study investigated the capacity of a collagen mimetic peptide (CMP) to promote corneal epithelial healing after an acute wound. A 360o lamellar keratectomy was performed and wound closure was compared between treated and vehicle groups. Treatment with CMP increased adherence of the basal epithelium to the underlying substrate and enhanced density of epithelial cells. This may represent a novel therapeutic to heal corneal tissue by repairing underlying collagen after corneal injury.
Thomas CN, Bernardo-Colón A, Courtie E, Essex G, Rex TS, Blanch RJ, Ahmed Z.
Effects of intravitreal injection of siRNA against caspase-2 on retinal and optic nerve degeneration in air blast induced ocular trauma.
Sci Rep. 2021 Aug 19;11(1):16839.
Repeat exposure to over-pressure air causes optic nerve damage. Treatment with caspase-2 siRNA was protective, but only when given prior to injury. Notably, intravitreal injections given soon after injury increased intraocular inflammation, which counteracted the positive effect of caspase 2 siRNA.
Ehlers JP, Yeh S, Maguire MG, Smith JR, Mruthyunjaya P, Jain N, Kim LA, Weng CY, Flaxel CJ, Schoenberger SD, Kim SJ.
Intravitreal Pharmacotherapies for Diabetic Macular Edema: A Report by the American Academy of Ophthalmology.
Ophthalmology. 2021 Aug 23:S0161-6420(21)00520-0.
This is a review of the evidence on safety and efficacy of anti-VEGF and intravitreal corticosteroid pharmacotherapies for the treatment of macular edema (DME). The published literature indicates that intravitreal injections of anti-VEGF agents and corticosteroids are efficacious treatments for DME.
Daniels AB, Froehler MT, Kaczmarek JV, Bogan CM, Santapuram PR, Pierce JM, Chen SC, Schremp EA, Boyd KL, Tao YK, Calcutt MW, Koyama T, Richmond A, Friedman DL.
Efficacy, Toxicity, and Pharmacokinetics of Intra-Arterial Chemotherapy Versus Intravenous Chemotherapy for Retinoblastoma in Animal Models and Patients.
Transl Vis Sci Technol. 2021 Sep 1;10(11):10.
The goal of this study was to understand mechanisms underlying differences in efficacy and toxicity between intra-arterial chemotherapy and intravenous chemotherapy. Greater efficacy and lower systemic toxicity was associated with intra-arterial chemotherapy. This appeared to be attributable to the greater ocular-to-systemic drug concentration ratio compared with intravenous chemotherapy.
Zhou R, Pfister T, Liu Y, Chen Q, Donahue S.
Age does not influence the PPV of Vision Screening to detect ARF.
Ophthalmology. 2021 Sep 7:S0161-6420(21)00646-1.
Among 3114 children seen at Vanderbilt Eye Institute from 11/1/2017-3/1/2020, the positive predictive value of vision screening to detect Amblyopia Risk Factors was similar for children <3 and for those aged 3-5 years.
Berkowitz ST, Groth SL, Gangaputra S, Patel S.
Racial/Ethnic Disparities in Ophthalmology Clinical Trials Resulting in US Food and Drug Administration Drug Approvals From 2000 to 2020.
JAMA Ophthalmol. 2021 Jun; 139:629-637.
In this cohort study, Black, Hispanic or Latinx, and other non-White participants were underrepresented in clinical trials leading to FDA ophthalmology drug approvals compared with the expected disease burden and racial/ethnic distribution in the US. Although there was meaningful improvement from 2000 to 2020, further efforts to increase minority enrollment in clinical trials seem to be warranted.
DeRuyter NP, Taubenslag KJ, Tran UL.
Insect Foreign Body in a Boston Type I Keratoprosthesis.
Ophthalmology. 2021 Jul; 128:1078.
Clinical case report of a corneal transplant patient who presented for eye pain and foreign body sensation. She had a history of melting corneal ulcer requiring multiple corneal transplants and eventual Boston keratoprosthesis. The foreign bodies were removed without complication.
Tamez H, Patel SN.
Retinal Artery Occlusion After a Dog Bite in a 55-Year-Old Man.
JAMA Ophthalmol. 2021 Jul; 139:798-799.
Clinical case report of unilateral uveitis and 2 days of sudden vision loss along with self-reported light sensitivity and mild eye pain. An inferior hemicentral retinal artery occlusion was confirmed on intravenous fluorescein angiography. Notably, a dog bit the patient’s hand two months prior to presentation and was associated with a persistent cough, night sweats, and low-grade fevers despite two courses of antibiotics.
Risner ML, Pasini S, McGrady NR, D'Alessandro KB, Yao V, Cooper ML, Calkins DJ.
Neuroprotection by WldS depends on retinal ganglion cell type and age in glaucoma.
Molecular Neurodegeneration 2021 Jun; 16:36.
We found WldS protects dendritic morphology and light-evoked responses of RGCs that signal light onset, but not those that respond to light offset during IOP elevation. As expected, WldS preserves anterograde axon transport and spatial acuity in young adult mice, but its protection is significantly limited in aged mice.
Naguib S, Backstrom JR, Gil M, Calkins DJ, Rex TS.
Retinal oxidative stress activates the NRF2/ARE pathway: An early endogenous protective response to ocular hypertension.
Redox Biology 2021 Jun; 42:101883.
We found that the NRF2-KEAP1-ARE pathway is endogenously activated early in ocular hypertension due to phosphorylation of NRF2 by the PI3K/AKT pathway. Further, activation of this pathway slows the onset of axon degeneration and vision loss after IOP elevation. Exogenous activation of this pathway might be an effective neuroprotective approach.
Froehler MT, Feldman MJ, Poitras B, Daniels AB.
Angiographic investigation of orbital vascular variations in the rabbit and implications for endovascular intra-arterial chemotherapy models.
Journal of Neurointerventional Surgery 2021 Jun; 13:559-562.
We show that successful catheterization of the ophthalmic arteries in the rabbit can be readily accomplished with nuanced technique. The external ophthalmic artery is the dominant arterial supply in the majority of rabbit eyes. These findings allow for successful reproduction of ophthalmic artery catheterization studies of intra-arterial chemotherapy for retinoblastoma in rabbits.
Risner ML, Pasini S, Chamling X, McGrady NR, Goldberg JL, Zack DJ, Calkins DJ.
Intrinsic Morphologic and Physiologic Development of Human Derived Retinal Ganglion Cells In Vitro.
Transl Vis Sci Technol. 2021 Aug; 10:1.
Human pluripotent stem cells were chemically differentiated into hRGCs and cultured up to 7 weeks. We measured soma area, neurite complexity, synaptic protein, axon-related messenger RNA and protein, and voltage-dependent responses. We found that human RGCs develop up to 7 weeks after culture. Thus, the state of hRGC maturation should be accounted for in designing models and treatments for optic neuropathies.
Giblin MJ, Smith TE, Winkler G, Pendergrass HA, Kim MJ, Capozzi ME, Yang R, McCollum GW, Penn JS.
Nuclear factor of activated T-cells (NFAT) regulation of IL-1β-induced retinal vascular inflammation.
Biochim Biophys Acta Mol Basis Dis. 2021 Jul; 166238
Chronic low-grade retinal inflammation is an essential contributor to the pathogenesis of diabetic retinopathy (DR). We investigated the NFAT-dependency of IL-1β-induced inflammation in human Müller cells (hMC) and human retinal microvascular endothelial cells (hRMEC). Our data demonstrate the potential of NFAT inhibition to mitigate retinal inflammation secondary to diabetes.
Wu HJ, Mortlock DP, Kuchtey RW, Kuchtey J.
Altered Ocular Fibrillin Microfibril Composition in Mice With a Glaucoma-Causing Mutation of Adamts10.
Invest Ophthalmol Vis Sci. 2021 Aug; 62:26.
Previously, we identified a G661R mutation of ADAMTS10 (a disintegrin-like and metalloprotease with thrombospondin type 1 motif 10) as being disease causative in a colony of Beagles with inherited primary open-angle glaucoma (POAG). Here we show that Adamts10G661R/G661R mice recapitulate the short stature and ocular phenotypes of Weill-Marchesani syndrome (WMS). The altered fibrillin-1 and fibrillin-2 immunoactivity in Adamts10G661R/G661R mice suggests that the G661R mutation of Adamts10 perturbs regulation of the fibrillin isotype composition of microfibrils in the mouse eye.
Day HR Jr, Breazzano MP, Bloch KC, et al. Response to Kato et al.: Prevalence of, and risk factors for, hematogenous fungal endophthalmitis in patients with Candida bloodstream infection. Infection 2019;47:501–502. Available at: http://dx.doi.org/10.1007/s15010-019-01289-3.
Breazzano MP, Milam RW Jr, Donahue SP. Repeated ophthalmic self-penetration with defecated needles. Am J Ophthalmol Case Rep 2019;14:19–20. Available at: http://dx.doi.org/10.1016/j.ajoc.2019.01.015.
Care RA, Kastner DB, De la Huerta I, et al. Partial Cone Loss Triggers Synapse-Specific Remodeling and Spatial Receptive Field Rearrangements in a Mature Retinal Circuit. Cell Rep 2019;27:2171–2183.e5. Available at: http://dx.doi.org/10.1016/j.celrep.2019.04.065.
Patel SN, Groth S, Sternberg P Jr. The Emergence of Private Equity in Ophthalmology. JAMA Ophthalmol 2019. Available at: http://dx.doi.org/10.1001/jamaophthalmol.2019.0964.
Gordon AY, Lapierre-Landry M, Skala MC, Penn JS. Photothermal Optical Coherence Tomography of Anti-Angiogenic Treatment in the Mouse Retina Using Gold Nanorods as Contrast Agents. Transl Vis Sci Technol 2019;8:18. Available at: http://dx.doi.org/10.1167/tvst.8.3.18.
Donahue SP, Sternberg P Jr. Improving Same-Day Access in Ophthalmology. JAMA Ophthalmol 2019. Available at: http://dx.doi.org/10.1001/jamaophthalmol.2019.0915.
Noble CW, Gangaputra SS, Thompson IA, et al. Ocular Adverse Events following Use of Immune Checkpoint Inhibitors for Metastatic Malignancies. Ocul Immunol Inflamm 2019:1–6. Available at: http://dx.doi.org/10.1080/09273948.2019.1583347.
Breazzano MP, Day HR Jr, Bloch KC, et al. Utility of Ophthalmologic Screening for Patients With Candida Bloodstream Infections: A Systematic Review. JAMA Ophthalmol 2019. Available at: http://dx.doi.org/10.1001/jamaophthalmol.2019.0733.
Patel SN, Snyder LL. REVERSE SUTURE TECHNIQUE FOR INTRAOCULAR LENS REFIXATION. Retin Cases Brief Rep 2019. Available at: http://dx.doi.org/10.1097/ICB.0000000000000867.
Wladis EJ, Aakalu VK, Tao JP, et al. Monocanalicular Stents in Eyelid Lacerations: A Report by the American Academy of Ophthalmology. Ophthalmology 2019. Available at: http://dx.doi.org/10.1016/j.ophtha.2019.03.045.
Thompson IA, Durrani AK, Patel S. Optical coherence tomography angiography characteristics in diabetic patients without clinical diabetic retinopathy. Eye 2019;33:648–652. Available at: http://dx.doi.org/10.1038/s41433-018-0286-x.
Sponsel WE, Groth S, March de Ribot F, et al. Efficacy of a Novel Retrobulbar Extension Shunt to Rescue Eyes with Fibrotic Encapsulated Blebs and Uncontrolled Ocular Hypertension. Graefes Arch Clin Exp Ophthalmol 2019;257:791–798. Available at: http://dx.doi.org/10.1007/s00417-018-4186-3.
Umfress AC, Mawn LA, Joos KM. Short-term Optic Disc Cupping Reversal in a Patient With Mild Juvenile Open-angle Glaucoma Due to Early Idiopathic Intracranial Hypertension. J Glaucoma 2019;28:e53–e57. Available at: http://dx.doi.org/10.1097/IJG.0000000000001151.
Daniels AB, Froehler MT, Nunnally AH, et al. Rabbit Model of Intra-Arterial Chemotherapy Toxicity Demonstrates Retinopathy and Vasculopathy Related to Drug and Dose, Not Procedure or Approach. Invest Ophthalmol Vis Sci 2019;60:954–964. Available at: http://dx.doi.org/10.1167/iovs.18-25346.
Jonna G, Daniels AB. Enhanced Depth Imaging OCT of Ultrasonographically Flat Choroidal Nevi Demonstrates 5 Distinct Patterns. Ophthalmol Retina 2019;3:270–277. Available at: http://dx.doi.org/10.1016/j.oret.2018.10.004.
Lou AY, Wannemuehler TJ, Russell PT, et al. Orbital apex syndrome caused by Alternaria species: A novel invasive fungus and new treatment paradigm. Orbit 2019:1–4. Available at: http://dx.doi.org/10.1080/01676830.2019.1582071.
Shah AA, Ling J, Nathan NR, et al. Long-term intraocular pressure changes after femtosecond laser-assisted cataract surgery in healthy eyes and glaucomatous eyes. J Cataract Refract Surg 2019;45:181–187. Available at: http://dx.doi.org/10.1016/j.jcrs.2018.08.037.
Johnson DB, Bao R, Ancell KK, et al. Response to Anti-PD-1 in Uveal Melanoma Without High-Volume Liver Metastasis. J Natl Compr Canc Netw 2019;17:114–117. Available at: http://dx.doi.org/10.6004/jnccn.2018.7070.
Pediatric Eye Disease Investigator Group, Writing Committee, Donahue SP, et al. A Randomized Trial Comparing Bilateral Lateral Rectus Recession versus Unilateral Recess and Resect for Basic-Type Intermittent Exotropia. Ophthalmology 2019;126:305–317. Available at: http://dx.doi.org/10.1016/j.ophtha.2018.08.034.
Daniels AB, Veverka KK, Patel SN, et al. Computing uveal melanoma basal diameters: a comparative analysis of several novel techniques with improved accuracy. Int J Retina Vitreous 2019;5:2. Available at: http://dx.doi.org/10.1186/s40942-018-0151-x.
Bakri SJ, Thorne JE, Ho AC, et al. Safety and Efficacy of Anti-Vascular Endothelial Growth Factor Therapies for Neovascular Age-Related Macular Degeneration: A Report by the American Academy of Ophthalmology. Ophthalmology 2019;126:55–63. Available at: http://dx.doi.org/10.1016/j.ophtha.2018.07.028.
Das S, Pineda G, Goff L, et al. The eye of the beholder: orbital metastases from midgut neuroendocrine tumors, a two institution experience. Cancer Imaging 2018;18:47. Available at: http://dx.doi.org/10.1186/s40644-018-0181-5.
Uddin MI, Kilburn TC, Yang R, et al. Targeted Imaging of VCAM-1 mRNA in a Mouse Model of Laser-Induced Choroidal Neovascularization Using Antisense Hairpin-DNA-Functionalized Gold-Nanoparticles. Mol Pharm 2018;15:5514–5520. Available at: http://dx.doi.org/10.1021/acs.molpharmaceut.8b00661.
Lavin P, Patrylo M, Hollar M, et al. Stroke Risk and Risk Factors in Patients With Central Retinal Artery Occlusion. Am J Ophthalmol 2018;196:96–100. Available at: http://dx.doi.org/10.1016/j.ajo.2018.08.027.
Breazzano MP, Day HR Jr, Tanaka S, Tran U. Prospective analysis of pediatric ocular chemical burns: laundry detergent pods. J AAPOS 2018;22:426–428. Available at: http://dx.doi.org/10.1016/j.jaapos.2018.07.349.
Love HD, Ao M, Jorgensen S, et al. Substrate Elasticity Governs Differentiation of Renal Tubule Cells in Prolonged Culture. Tissue Eng Part A 2018. Available at: http://dx.doi.org/10.1089/ten.TEA.2018.0182.
Bernardo-Colón A, Vest V, Clark A, et al. Antioxidants prevent inflammation and preserve the optic projection and visual function in experimental neurotrauma. Cell Death Dis 2018;9:1097. Available at: http://dx.doi.org/10.1038/s41419-018-1061-4.
Lu JE, Francis JH, Dunkel IJ, et al. Metastases and death rates after primary enucleation of unilateral retinoblastoma in the USA 2007-2017. Br J Ophthalmol 2018. Available at: http://dx.doi.org/10.1136/bjophthalmol-2018-312915.
Silverstein E, Donahue SP. Preschool Vision Screening: Where We Have Been and Where We Are Going. Am J Ophthalmol 2018;194:xviii–xxiii. Available at: http://dx.doi.org/10.1016/j.ajo.2018.07.022.
Hsu ST, Perry I, Botsay S, et al. Characterization of Corneal Donor Tissue Lesions by Anterior Segment Optical Coherence Tomography Compared With Eye Bank Technician Slit-Lamp Examination. Cornea 2018;37:1318–1323. Available at: http://dx.doi.org/10.1097/ICO.0000000000001700.
Mitchell SL, Uppal K, Williamson SM, et al. The Carnitine Shuttle Pathway is Altered in Patients With Neovascular Age-Related Macular Degeneration. Invest Ophthalmol Vis Sci 2018;59:4978–4985. Available at: http://dx.doi.org/10.1167/iovs.18-25137.
Chaganti S, Nelson K, Mundy K, et al. Imaging biomarkers in thyroid eye disease and their clinical associations. J Med Imaging (Bellingham) 2018;5:044001. Available at: http://dx.doi.org/10.1117/1.JMI.5.4.044001.
Snyder L, Patel S. Laser Pointer Maculopathy. Ophthalmol Retina 2018;2:996. Available at: http://dx.doi.org/10.1016/j.oret.2018.07.004.
Breazzano MP, Kim SJ. Leukemic Ophthalmoplegia with Combined Central Retinal Artery/Vein Occlusions. Ophthalmol Retina 2018;2:1070. Available at: http://dx.doi.org/10.1016/j.oret.2018.08.001.
Aziz M, Patel S. BB Gun-Related Open Globe Injuries. Ophthalmol Retina 2018;2:1056–1061. Available at: http://dx.doi.org/10.1016/j.oret.2018.03.006.
Wladis EJ, Aakalu VK, Yen MT, et al. Balloon Dacryoplasty for Congenital Nasolacrimal Duct Obstruction: A Report by the American Academy of Ophthalmology. Ophthalmology 2018;125:1654–1657. Available at: http://dx.doi.org/10.1016/j.ophtha.2018.05.005.
Breazzano MP, Day HR Jr, Tanaka S, Tran U. CLEARED (Chemicals and Litmus testing with Effective Alkaline Range for Eye Damage): A Prospective, Interventional Study. Acad Emerg Med 2018. Available at: http://dx.doi.org/10.1111/acem.13622.
Jonna G, Thompson IA, Mendel TA, Kim SJ. FIVE-YEAR FUNCTIONAL OUTCOMES AFTER EPIRETINAL MEMBRANE SURGERY: A Prospective, Controlled Study. Retina 2018. Available at: http://dx.doi.org/10.1097/IAE.0000000000002323.
Wu H-J, Hazlewood RJ, Kuchtey J, Kuchtey RW. Enlarged Optic Nerve Axons and Reduced Visual Function in Mice with Defective Microfibrils. eNeuro 2018;5. Available at: http://dx.doi.org/10.1523/ENEURO.0260-18.2018.
Johnson DB, Daniels AB. Continued Poor Survival in Metastatic Uveal Melanoma: Implications for Molecular Prognostication, Surveillance Imaging, Adjuvant Therapy, and Clinical Trials. JAMA Ophthalmol 2018;136:986–988. Available at: http://dx.doi.org/10.1001/jamaophthalmol.2018.1813.
Bilyk JR, Yen MT, Bradley EA, et al. Chemodenervation for the Treatment of Facial Dystonia: A Report by the American Academy of Ophthalmology. Ophthalmology 2018;125:1459–1467. Available at: http://dx.doi.org/10.1016/j.ophtha.2018.03.013.
Arnold RW, O’Neil JW, Cooper KL, et al. Evaluation of a smartphone photoscreening app to detect refractive amblyopia risk factors in children aged 1-6 years. Clin Ophthalmol 2018;12:1533–1537. Available at: http://dx.doi.org/10.2147/OPTH.S171935.
Johnson KB, Sternberg P Jr, Dubree M. An EPIC Switch: Observations and Opportunities After Go-Live. J Med Syst 2018;42:174. Available at: http://dx.doi.org/10.1007/s10916-018-1023-5.
Ferguson DC, Mawn LA, Al-Rohil RN. Cutaneous Angiosarcoma of the Eyelid Mimicking Morbihan Disease. Am J Dermatopathol 2018;40:617–620. Available at: http://dx.doi.org/10.1097/DAD.0000000000001096.
Patel S. Medicare Spending on Anti-Vascular Endothelial Growth Factor Medications. Ophthalmol Retina 2018;2:785–791. Available at: http://dx.doi.org/10.1016/j.oret.2017.12.006.
Copperman TS, Truong MT, Berk JL, Sobel RK. External beam radiation for localized periocular amyloidosis: a case series. Orbit 2018:1–7. Available at: http://dx.doi.org/10.1080/01676830.2018.1483407.
Breazzano MP, Nickols HH, Daniels AB. Lung Adenocarcinoma Metastatic to Iris and Angle with Pseudokeratic Precipitates. Ophthalmol Retina 2018;2:605. Available at: http://dx.doi.org/10.1016/j.oret.2018.02.009.
Keller KE, Bhattacharya SK, Borrás T, et al. Consensus recommendations for trabecular meshwork cell isolation, characterization and culture. Exp Eye Res 2018;171:164–173. Available at: http://dx.doi.org/10.1016/j.exer.2018.03.001.
Esfandiari H, Shazly TA, Waxman SA, et al. Similar Performance of Trabectome and Ahmed Glaucoma Devices in a Propensity Score-matched Comparison. J Glaucoma 2018;27:490–495. Available at: http://dx.doi.org/10.1097/IJG.0000000000000960.
Tamez HM, Tauscher R, Brown EN, et al. Rate of Unverifiable Publications Among Ophthalmology Residency Applicants Invited to Interview. JAMA Ophthalmol 2018;136:630–635. Available at: http://dx.doi.org/10.1001/jamaophthalmol.2018.0846.
Garcia KL, Breazzano MP, Bond JB 3rd, et al. A 3-Year-Old With Sudden-Onset Anisocoria After Playing Outside. Pediatr Emerg Care 2018;34:e111–e114. Available at: http://dx.doi.org/10.1097/PEC.0000000000001513.
Tan B, Gurdita A, Choh V, et al. Morphological and functional changes in the rat retina associated with 2 months of intermittent moderate intraocular pressure elevation. Sci Rep 2018;8:7727. Available at: http://dx.doi.org/10.1038/s41598-018-25938-z.
Cooper ML, Collyer JW, Calkins DJ. Astrocyte remodeling without gliosis precedes optic nerve Axonopathy. Acta Neuropathol Commun 2018;6:38. Available at: http://dx.doi.org/10.1186/s40478-018-0542-0.
Donahue SP. Studies Omitted From the US Preventive Services Task Force Recommendations for Child Vision Screening-Reply. JAMA Ophthalmol 2018;136:600–601. Available at: http://dx.doi.org/10.1001/jamaophthalmol.2018.0633.
Patel S, Sternberg P Jr. Avoid Compromises in the Current Opioid Crisis, Using Cautious but Confident Patient Care-Reply. JAMA Ophthalmol 2018;136:595–596. Available at: http://dx.doi.org/10.1001/jamaophthalmol.2018.0636.
Capozzi ME, Giblin MJ, Penn JS. Palmitic Acid Induces Müller Cell Inflammation that is Potentiated by Co-treatment with Glucose. Sci Rep 2018;8:5459. Available at: http://dx.doi.org/10.1038/s41598-018-23601-1.
Drewry MD, Challa P, Kuchtey JG, et al. Differentially expressed microRNAs in the aqueous humor of patients with exfoliation glaucoma or primary open-angle glaucoma. Hum Mol Genet 2018;27:1263–1275. Available at: http://dx.doi.org/10.1093/hmg/ddy040.
Risner ML, Pasini S, Cooper ML, et al. Axogenic mechanism enhances retinal ganglion cell excitability during early progression in glaucoma. Proc Natl Acad Sci U S A 2018;115:E2393–E2402. Available at: http://dx.doi.org/10.1073/pnas.1714888115.
Patel SN, Kim SJ. White Retinal Lesions in a Patient With Leukemia. JAMA Ophthalmol 2018;136:301–302. Available at: http://dx.doi.org/10.1001/jamaophthalmol.2017.4333.
Braue JA, Daniels AB, Zwerner JP, et al. Intraocular involvement of mycosis fungoides associated with immunophenotypic switch from CD4+ to CD8. Blood 2018;131:932–935. Available at: http://dx.doi.org/10.1182/blood-2017-11-814194.
Arreola A, Payne LB, Julian MH, et al. Von Hippel-Lindau mutations disrupt vascular patterning and maturation via Notch. JCI Insight 2018;3. Available at: http://dx.doi.org/10.1172/jci.insight.92193.
Sternberg P Jr, Durrani AK. Evolving Concepts in the Management of Retinopathy of Prematurity. Am J Ophthalmol 2018;186:xxiii–xxxii. Available at: http://dx.doi.org/10.1016/j.ajo.2017.10.027.
Reddy AC, Portilla A, Donahue SP. Purely horizontal strabismus associated with head tilt. J AAPOS 2018;22:69–71. Available at: http://dx.doi.org/10.1016/j.jaapos.2017.09.008.
Youn TS, Lavin P, Patrylo M, et al. Current treatment of central retinal artery occlusion: a national survey. J Neurol 2018;265:330–335. Available at: http://dx.doi.org/10.1007/s00415-017-8702-x.
Durrani AK, Mehta VJ, Kim SJ. Postinfluenza Purtscher-like Retinopathy with Acute Macular Neuroretinopathy. Ophthalmol Retina 2018;2:95. Available at: http://dx.doi.org/10.1016/j.oret.2017.09.020.
Law JC, Golnik KC, Cherney EF, et al. The Ophthalmology Surgical Competency Assessment Rubric for Panretinal Photocoagulation. Ophthalmol Retina 2018;2:162–167. Available at: http://dx.doi.org/10.1016/j.oret.2017.06.002.
Wladis EJ, Aakalu VK, Sobel RK, et al. Orbital Implants in Enucleation Surgery: A Report by the American Academy of Ophthalmology. Ophthalmology 2018;125:311–317. Available at: http://dx.doi.org/10.1016/j.ophtha.2017.08.006.
Mawn LA, Dolman PJ, Kazim M, et al. Soft Tissue Metrics in Thyroid Eye Disease: An International Thyroid Eye Disease Society Reliability Study. Ophthal Plast Reconstr Surg 2018;34:544–546. Available at: http://dx.doi.org/10.1097/IOP.0000000000001080.
Mehta VJ, Chelnis JG, Chen Q, Mawn LA. Effect of Time to Operative Intervention on Motility Outcomes Following Orbital Floor Fracture Repair in Children. Ophthal Plast Reconstr Surg 2018;34:351–354. Available at: http://dx.doi.org/10.1097/IOP.0000000000000993.
De Niear MA, Breazzano MP, Mawn LA. Novel FOXC2 Mutation and Distichiasis in a Patient With Lymphedema-Distichiasis Syndrome. Ophthal Plast Reconstr Surg 2018;34:e88–e90. Available at: http://dx.doi.org/10.1097/IOP.0000000000001079.
Daniels AB, Froehler MT, Pierce JM, et al. Pharmacokinetics, Tissue Localization, Toxicity, and Treatment Efficacy in the First Small Animal (Rabbit) Model of Intra-Arterial Chemotherapy for Retinoblastoma. Invest Ophthalmol Vis Sci 2018;59:446–454. Available at: http://dx.doi.org/10.1167/iovs.17-22302.
Siatkowski RM, Mian SI, Culican SM, et al. Probability of Success in the Ophthalmology Residency Match: Three-Year Outcomes Analysis of San Francisco Matching Program Data. J Acad Ophthalmol 2018;10:e150–e157. Available at: http://dx.doi.org/10.1055/s-0038-1673675.
Fathy CA, Pichert JW, Domenico H, et al. Association Between Ophthalmologist Age and Unsolicited Patient Complaints. JAMA Ophthalmol 2018;136:61–67. Available at: http://dx.doi.org/10.1001/jamaophthalmol.2017.5154.
Lindsey JL, Sternberg P Jr. Presence of Trainees and Appointment Times. JAMA Ophthalmol 2018;136:27–28. Available at: http://dx.doi.org/10.1001/jamaophthalmol.2017.4785.
Calkins DJ, Lambert WS, Formichella CR, et al. The Microbead Occlusion Model of Ocular Hypertension in Mice. Methods Mol Biol 2018;1695:23–39. Available at: http://dx.doi.org/10.1007/978-1-4939-7407-8_3.
Uddin MI, Jayagopal A, Wong A, et al. Real-time imaging of VCAM-1 mRNA in TNF-α activated retinal microvascular endothelial cells using antisense hairpin-DNA functionalized gold nanoparticles. Nanomedicine 2018;14:63–71. Available at: http://dx.doi.org/10.1016/j.nano.2017.08.018.
Jonna G, Kim SJ. Re: Singh et al.: Nepafenac 0.3% after cataract surgery in patients with diabetic retinopathy: results of 2 randomized phase 3 studies (Ophthalmology. 2017;124:776-785). Ophthalmology 2018;125:e4. Available at: http://dx.doi.org/10.1016/j.ophtha.2017.07.023.
Yen MT, Bilyk JR, Wladis EJ, et al. Treatments for Ocular Adnexal Lymphoma: A Report by the American Academy of Ophthalmology. Ophthalmology 2018;125:127–136. Available at: http://dx.doi.org/10.1016/j.ophtha.2017.05.037.
Note: This list was generated by a complex PubMed search that was then curated to remove non-VEI publications. Some may still have escaped the hand-curation.