Castilho JL, Turner M, Shepherd BE, Koethe JR, Furukawa SS, Bofill CE, Raffanti SP, Sterling TR. CD4/CD8 ratio and CD4 nadir predict mortality following non-communicable disease diagnosis in adults living with HIV. AIDS research and human retroviruses. 2019 Aug 13. PMID: 31407605 [PubMed]
Incidence of non-communicable diseases (NCDs) including cardiovascular disease (CVD), cirrhosis, and non-AIDS-defining cancers (NADCs) have been associated with HIV viremia, CD4 cell counts and CD4/CD8 ratio in persons living with HIV. This study examined the importance of these markers to mortality risk following NCD diagnosis.