This grant has ended and is part of our past portfolio of work.
Principal Investigator(s):
Marcia L. Kalish, Ph.D.
Phylogenetic Characterization the HIV-1 Epidemic in Middle Tennessee, CFAR Supplement (P30AI110527)
Understanding HIV transmission dynamics is critical for implementing targeted testing, treatment and prevention, and successful modification and public access to the 'nextHIV' program will have utility for health departments and organizations beyond middle Tennessee. This project is using retrospective phylogenetic, socio-demographic, and clinical data to characterize the HIV-1 epidemic in middle Tennessee. We will assess the extent to which continued HIV transmission is driven by local social/sexual networks or introductions from outside this area. In addition, the project aims to develop a near real-time tracking system for HIV phylodynamics ('nextHIV'), based on the 'nextstrain' platform.