Buche A, Ouassaidi A, Hacha R, Delpire E, Gilles R, Houssier C. Glycine and other amino compounds prevent chromatin precipitation at physiological ionic strength. FEBS letters. 1989 Apr 24;247(247). 367-70. PMID: 2714440 [PubMed]
Glycine, proline and taurine, when present in the range 0.1-0.60 M, inhibit chromatin precipitation by sodium chloride. Histone gel electrophoresis revealed that the linker histones H1 and H5 were largely depleted from the supernatant chromatin fraction at 0.2 M NaCl, while this depletion was absent in the presence of glycine. These observations are discussed in relation with the various factors which may be involved in the precipitation process.