Phenome-wide association studies uncover a novel association of increased atrial fibrillation in males with systemic lupus erythematosus.

Barnado A, Carroll RJ, Casey C, Wheless L, Denny JC, Crofford LJ. Phenome-wide association studies uncover a novel association of increased atrial fibrillation in males with systemic lupus erythematosus. Arthritis care & research. 2018 Feb 26. PMID: 29481723 [PubMed]

Abstract

Phenome-wide association studies (PheWAS) scan across billing codes in the electronic health record (EHR) and re-purpose clinical EHR data for research. We examined if PheWAS could function as an EHR discovery tool for SLE and uncover novel clinical associations in male versus female SLE patients.