Genotype and risk of major bleeding during warfarin treatment.

Kawai VK, Cunningham A, Vear SI, Van Driest SL, Oginni A, Xu H, Jiang M, Li C, Denny JC, Shaffer C, Bowton E, Gage BF, Ray WA, Roden DM, Stein CM. Genotype and risk of major bleeding during warfarin treatment. Pharmacogenomics. 2014 Dec;15(15). 1973-83. PMID: 25521356 [PubMed] PMCID: PMC4304738 NIHMSID: NIHMS652646.

Abstract

To determine whether genetic variants associated with warfarin dose variability were associated with increased risk of major bleeding during warfarin therapy.