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Iwuchukwu OF, Ramirez AH, Shi Y, Bowton EA, Kawai VK, Schildcrout JS, Roden DM, Denny JC, Stein CM. Genetic determinants of variability in warfarin response after the dose-titration phase. Pharmacogenetics and genomics. 2016 Nov;26(26). 510-516. NIHMSID: NIHMS812381.
Abstract
Genetic factors contribute considerably toward variability in warfarin dose requirements and are important in the dose-titration phase; their effects on the stability of anticoagulation later in therapy are not known.