MEDI--an Ensemble MEDication Indication Resource

MEDI (MEDication Indication) is an ensemble medication indication resource for primary and secondary uses of electronic medical record (EMR) data.  MEDI was created based on multiple commonly used medication resources (RxNorm, MedlinePlus, SIDER 2, and Wikipedia ) and by leveraging both ontology and natural language processing (NLP) techniques. 

MEDI contains 3,112 medications and 63,343 medication-indication pairs. The MEDI high precision subset (MEDI-HPS) includes indications found within either RxNorm or at least two of the three other resources. MEDI-HPS contains ~13,400 unique indication pairs regarding 2,136 medications. The average (±standard deviation) number of indications for each medication in MEDI-HPS is 6.22±6.09. The mode for each medication is 2 while the median is 4. The estimated precision MEDI-HPS is >92% based on physician review.

The download of MEDI is for free. Right click and select the download linked file or similar option in your browser to save the files on your computer.


MEDI_HPS.csv (High Precision Set)

MEDI_UMLS.csv (including RxCUI, UMLS, ATC, NDDF concepts and their indications)




MEDI by Dr. Wei-Qi Wei & Dr. Joshua Denny is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License.

Key references:
1. WQ Wei, RM Cronin, H Xu, TA Lasko, L Bastarache, JC Denny, Development and evaluation of an ensemble resource linking medications to their indications, Journal of the American Medical Informatics Association. 2013;20:954-961 doi:10.1136/amiajnl-2012-001431
2. WQ Wei, JD Mosley et al. Validation and Enhancement of a Computable Medication Indication Resource (MEDI) Using a Large Practice-based Dataset. AMIA Annual Symposium, 2013, Washington DC.