Jackson K, Anderson V, Zhao Z, Kitko CL, Connelly JA, Ho RH, Banerjee R, Dulek DE, Friedman DL, Esbenshade AJ. Applying a risk prediction model for bloodstream infection in a febrile, nonseverely neutropenic cohort of pediatric stem cell transplant patients. Cancer. 2023 May 15;129(129). 1591-1601. PMID: 36828805 [PubMed]
The optimal management of febrile stem cell transplant (SCT) patients presenting without severe neutropenia (absolute neutrophil count [ANC] ≥ 500/µL) is unclear. The authors have developed iterative risk prediction models (Esbenshade Vanderbilt [EsVan] models) that reliably predict bloodstream infections (BSIs) in the febrile general pediatric oncology population without severe neutropenia, but SCT-specific data are limited.