Vanderbilt TB Center News

VTC Hosts LTBI R01 Meeting

The Vanderbilt Tuberculosis Center recently hosted a meeting of researchers involved in our LTBI R01 project “Immunogenetic predictors of active and incipient TB in HIV-negative and -positive close TB contacts” (NIH R01AI147765). The event, which took place between March 21st and 22nd, and included presentations about ongoing research and data findings, working group sessions, and breakout meetings.

RePORT-Brazil Investigators at CROI 2024

The 2024 Conference on Retroviruses and Opportunistic Infections (CROI) in Denver was attended by investigators from RePORT-Brazil, including presentations on recent findings and articles. Poster Presentations:Dr. Gustavo Amorim, PhD - "Estimating Optimal Anti-TB Drug Concentrations in a Prospective, Observational Cohort in Brazil"Dr. Felipe Ridolfi, PhD, MD - “Pharmacogenetic Associations With HIV-1 Virologic Suppression Among Patients with TB/HIV in Brazil”

RePORT-Brazil in the Spotlight - CID Article

A recently publication in the journal Clinical Infectious Diseases is catching attention. The Xpert® MTB/RIF cycle threshold value predicts M. tuberculosis transmission to close contacts in a Brazilian prospective multicenter cohort  was published by the RePORT-Brazil consortium, with authorship being led by the team at the Fundação de Medicina Tropical in Manaus, Amazonas, Brazil.  

TBTC Launches CRUSH-TB trial

CDC’s Tuberculosis Trials Consortium (TBTC) has recently launched the CRUSH-TB trial, which aims to identify new combinations of drugs to shorten treatment of active TB disease. Kelly Dooley, MD, PhD, MPH, Director, Division of Infectious Diseases, is a Protocol Chair for this new study. Read more from CDC’s TB Notes newsletter:

TB Center welcomes 1st Cohort of RePORT-Brazil Advanced Career Training (ReACT) Fellows

The Regional Prospective Observational Research in Tuberculosis - Brazil (RePORT-Brazil) network is pleased to announce its 1st Cohort of Fellows for the RePORT-Brazil Advanced Career Training (ReACT) program. Strategic Aim 3 of the recently renewed RePORT-Brazil Phase 2 grant (NIH U01AI172064-01), focuses on the development of a fellowship program for the advancement of early-career Brazilian scientists. The program provides funding for pilot projects in TB research, mentorship, and access to data and specimens collected throughout Phase 1 of the project.

Aurum Leadership Visit VUMC

Prof. Gavin Churchyard, CEO; Mr. Arshad Hassim, CFO; and Dr. Violet Chihota, Chief Specialist Scientist of the Aurum Institute, visited VUMC from August 21st to August 25th. Their visit strengthens the ongoing collaborative partnership between the two institutions, which is focused on research and global health. Included in the visit were a variety of strategic planning meetings, programmatic evaluations, and a presentation at ID Grand Rounds by Dr. Violet Chihota.

Dr. María Belen Arriaga Gutiérrez receives 2023 CAPES Thesis Award

Dr. María Belen Arriaga Gutiérrez, post-doctoral scholar at the Vanderbilt Tuberculosis Center, recently received commendations for her doctoral thesis "Clinical and Epidemiologic Determinants of Susceptibility to Infection by Mycobacterium tuberculosis and the Therapeutic Responses in Patients with Tuberculosis” from the Brazilian Department of Education and CAPES, Coordination for the Improvement of Higher Education.

VTC Hosts TB/HIV R01 Meeting

Vanderbilt Tuberculosis Center recently hosted a meeting of researchers involved in our TB/HIV grant "Predictors of treatment toxicity, failure, and relapse in HIV-related tuberculosis" (NIH R01AI120790-04). The event, which took place on April 26th and 27th, included presentations on the results and findings of each working group, breakout sessions, and discussions on future steps to be taken and larger goals of the research.