Vanderbilt TB Center News

VTC hosts visitors from Brazil, South Africa, UW for grant project meeting

Vanderbilt Tuberculosis Center recently hosted a meeting of researchers involved in our LTBI R01 project “Immunogenetic predictors of active and incipient TB in HIV-negative and -positive close TB contacts” (NIH R01AI147765). The event, which took place between May 31st and June 2nd, included presentations about ongoing research and initial data, working group sessions, and breakout meetings.

Results Published: Randomized Trial for Self-administered vs DOT Once-Weekly Isoniazid and Rifapentine Treatment of Latent TB Infection

Results from the iAdhere trial conducted through the TB Trials Consortium have been published in the Annals of Internal Medicine. This randomized trial aimed to compare treatment completion and safety of once-weekly isoniazid and rifapentine by self-administration versus direct observation. Enrollment sites were located in the US, Spain, Hong Kong, and South Africa; Vanderbilt and the Metro Nashville Health Department participated in enrollment.