Andrews B, Muchemwa L, Kelly P, Lakhi S, Heimburger DC, Bernard GR. Simplified severe sepsis protocol: a randomized controlled trial of modified early goal-directed therapy in Zambia. Critical care medicine. 2014 Nov;42(42). 2315-24. PMID: 25072757 [PubMed] PMCID: PMC4199893 NIHMSID: NIHMS604412.
To assess the efficacy of a simple, goal-directed sepsis treatment protocol for reducing mortality in patients with severe sepsis in Zambia.