May 12, 2017

Principal Investigator(s): 
Carolyn Audet, Ph.D.

Partners-based HIV Treatment for Sero-concordant Couples attending Antenatal Care (R01 MH113478-01)
The purpose of this R01 proposal is to evaluate the clinical impact, hypothesized mechanisms of behavior change, and cost-effectiveness of a partners-focused integrated elimination of mother-to-child transmission of HIV (PMTCT) package comprised of: 1) antenatal care-based couples HIV testing, ART enrollment, and care for sero-concordant HIV+ expectant couples; (2) Couples-based treatment in the post-partum period; (3) Couple-based education and skills building; and (4) Treatment continuity with the support of expert-patient (peer) supporters from couples who have successfully navigated PMTCT. This innovative approach to scaling up PMTCT services, if proven feasible and effective, will be adopted in PEPFAR programs to accelerate progress toward PMTCT and helping families with HIV infection live long, healthy lives.