Norovirus earned its name as the "perfect pathogen"because it spreads faster and farther than most viruses, infecting 20 million people in the United States every year and killing 200,000 worldwide. Although the virus - the leading cause of gastrointestinal illness - survives typical disinfectants and is constantly changing, researchers at Vanderbilt University have taken a step toward developing a vaccine and toward improving diagnosis and treatment.
The United States Patent and Trademark Office (USPTO) announced the 2018 Patents for Humanity winners with Vanderbilt University awarded an honorable mention.
Researchers at Vanderbilt University Medical Center and their colleagues are a step closer to developing a broadly effective antibody treatment against the three major Ebola viruses that cause lethal disease in humans. Reporting July 17 in the journal Immunity, they describe the isolation of two potent monoclonal antibodies from human survivors of Ebola virus disease that, in cell culture studies, efficiently neutralized the Zaire, Sudan and Bundibugyo ebolaviruses.
Finally, anti-bodies to three major Ebola viruses have now been developed. Researchers at Vanderbilt University Medical Center are a step closer to developing a broadly effective antibody treatment against these viruses that cause the lethal disease in humans. Researchers found that the isolation of two potent monoclonal antibodies from human survivors of Ebola virus disease in cell culture studies efficiently neutralized the Zaire, Sudan and Bundibugyo Ebola viruses.
Two types of antibodies from the blood of Ebola survivors protected animals against strains of the virus that cause deadly infections in people, researchers report. It may be possible to use these antibodies to create a treatment for Ebola, the researchers said.
The laboratory of James Crowe Jr., MD, director of the Vanderbilt Vaccine Center, received the 2018 Vaccine Industry Excellence Award for Best Academic Research Team at the 18th World Vaccine Congress in Washington, DC, this week. The congress is an annual meeting of vaccine professionals from industry, academia and nonprofit organizations. The awards are given to recognize outstanding achievements by companies, research teams and individuals in the vaccine industry.