2026
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Fansler RT, Grote A, Langford-Butler M, Miller AK, Neal M, Hale OF, Wu Y, Singla D, Calcutt M, Rose AE, Bresson MM, Schrimpe-Rutledge AC, Berdy B, Codreanu SG, Washington MK, Bratton BP, Sherrod SD, McLean JA, Zengler K, Sears CL, Behringer MG, Gnirke A, Livny J, Olivares-Villagómez D, Earl AM, Zhu W. An Anaerobic Pathogen Rewires Host Metabolism to Fuel Oxidative Growth in the Inflamed Gut Cell.
2025
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Singla D, Rose A. Zhu W. Small intestine changes, large intestine problems Trends in Microbiology. 2025 Jan 30.
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Spencer PN, Wang J, Smith EP, Spiga L, Simmons AJ, Kim T, Kim W, Brown ME, Yang Y, Kaur H, Xu Y, Kang SW, Helou MD, Lee MA, Zheng L, Arceneaux D, Tasneem N, Mueller KD, Kuddar OS, Harned MH, Ro J, Li J, Banerjee A, Markham NO, Wilson KT, Coburn LA, Goettel JA, Liu Q, Kay Washington M, Valdivia RH, Zhu W, Lau KS. Pathobiont-triggered induction of epithelial IDO1 drives regional susceptibility to Inflammatory Bowel Disease. BioRxiv : the preprint server for biology. 2025 Jan 4.
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Rüttiger AS, Ryan D, Spiga L, Lamm-Schmidt V, Prezza G, Reichardt S, Langford M, Barquist L, Faber F, Zhu W, Westermann AJ. The global RNA-binding protein RbpB is a regulator of polysaccharide utilization in Bacteroides thetaiotaomicron. Nature communications. 2025 Jan 2;16(16). 208 p.
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Prezza G., Westermann A.J.. Fansler R.T., Guest T., Madler G., Zhu W.. Identification of an RNA regulator of mucus colonization and iron homeostasis in Bacteroides thetaiotaomicron BioRxiv.
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Fansler R.T., Wu Y., Zhu W.. Friend or Foe? Contextualizing Bacteroides Through the Lens of Niche Remodeling Trends in Microbiology.
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Fansler R.T., Rose A.E., Zhu W.. Commensal resilience: ancient ecological lessons for the modern microbiota Infection and Immunity.
2023
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Spiga L, Fansler T, Perera R. Shealy G, Munneke J, Torres P, David E, Lemoff A, Ran X, Richardson L, Pudlo N, Martens C, Yang J, Skaar P, Byndloss X, Chazin J, Zhu W. "Iron acquisition by a commensal bacterium modifies host nutritional immunity during Salmonella infection" Cell Host & Microbe. 2023 Jun 26.
2022
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Taylor SJ, Winter MG, Gillis CC, Silva LAD, Dobbins AL, Muramatsu MK, Jimenez AG, Chanin RB, Spiga L, Llano EM, Rojas VK, Kim J, Santos RL, Zhu W, Winter SE. Colonocyte-derived lactate promotes E. coli fitness in the context of inflammation-associated gut microbiota dysbiosis. Microbiome. 2022 Nov 26;10(10). 200 p.
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Jia H, Song N, Ma Y, Zhang F, Yue Y, Wang W, Li C, Li H, Wang Q, Gu L, Li B. Salmonella Facilitates Iron Acquisition through UMPylation of Ferric Uptake Regulator. MBio. 2022 Jun 28;13(13). e0020722.
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Fansler RT, Zhu W. Mind the Gap: Bridging the Divide from Sequencing Data to Empiric Phenotypes in the Human Gut Microbiota. MSystems. 2022 Jun 28;7(7). e0020722.
2021
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Hughes ER, Winter MG, Alves da Silva L, Muramatsu MK, Jimenez AG, Gillis CC, Spiga L, Chanin RB, Santos RL, Zhu W, Winter SE. Reshaping of bacterial molecular hydrogen metabolism contributes to the outgrowth of commensal during gut inflammation. ELife. 2021 Dec 4;10(10).
2020
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Ellermann M, Pacheco AR, Jimenez AG, Russell RM, Cuesta S, Kumar A, Zhu W, Vale G, Martin SA, Raj P, McDonald JG, Winter SE, Sperandio V. Endocannabinoids Inhibit the Induction of Virulence in Enteric Pathogens. Cell. 2020 Dec 29;183(183). 650-665.e15. NIHMSID: NIHMS1628418.
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Chanin RB, Winter MG, Spiga L, Hughes ER, Zhu W, Taylor SJ, Arenales A, Gillis CC, Büttner L, Jimenez AG, Smoot MP, Santos RL, Winter SE. Epithelial-Derived Reactive Oxygen Species Enable AppBCX-Mediated Aerobic Respiration of Escherichia coli during Intestinal Inflammation. Cell host & microbe. 2020 Dec 9;28(28). 780-788.e5. NIHMSID: NIHMS1628633.
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Menezes-Garcia Z, Kumar A, Zhu W, Winter SE, Sperandio V. l-Arginine sensing regulates virulence gene expression and disease progression in enteric pathogens. Proceedings of the National Academy of Sciences of the United States of America. 2020 Dec 2;117(117). 12387-12393.
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Zhu W, Winter MG, Spiga L, Hughes ER, Chanin R, Mulgaonkar A, Pennington J, Maas M, Behrendt CL, Kim J, Sun X, Beiting DP, Hooper LV, Winter SE. Xenosiderophore Utilization Promotes Bacteroides thetaiotaomicron Resilience during Colitis. Cell host & microbe. 2020 Feb 11.
2019
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Wilson RP, Tursi SA, Rapsinski GJ, Medeiros NJ, Le LS, Kotredes KP, Patel S, Liverani E, Sun S, Zhu W, Kilpatrick L, Winter SE, Gamero AM, Tükel Ç. STAT2 dependent Type I Interferon response promotes dysbiosis and luminal expansion of the enteric pathogen Salmonella Typhimurium. PLoS pathogens. 2019 Dec;15(15). e1007745.
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Zhu W, Spiga L, Winter S. Transition metals and host-microbe interactions in the inflamed intestine. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine. 2019 Dec;32(32). 369-384. NIHMSID: NIHMS1525030.
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Gillis CC, Winter MG, Chanin RB, Zhu W, Spiga L, Winter SE. Host-Derived Metabolites Modulate Transcription of Genes Involved in l-Lactate Utilization during Gut Colonization. Infection and immunity. 2019 Dec;87(87).
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Zhu W, Miyata N, Winter MG, Arenales A, Hughes ER, Spiga L, Kim J, Sifuentes-Dominguez L, Starokadomskyy P, Gopal P, Byndloss MX, Santos RL, Burstein E, Winter SE. Editing of the gut microbiota reduces carcinogenesis in mouse models of colitis-associated colorectal cancer. The Journal of experimental medicine. 2019 Oct 7;216(216). 2378-2393.
2018
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Gillis CC, Hughes ER, Spiga L, Winter MG, Zhu W, Furtado de Carvalho T, Chanin RB, Behrendt CL, Hooper LV, Santos RL, Winter SE. Dysbiosis-Associated Change in Host Metabolism Generates Lactate to Support Salmonella Growth. Cell host & microbe. 2018 Dec 11;23(23). 570 p. NIHMSID: NIHMS957248.
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Zhu W, Winter MG, Byndloss MX, Spiga L, Duerkop BA, Hughes ER, Büttner L, De Lima Romão E, Behrendt CL, Lopez CA, Sifuentes-Dominguez L, Huff-Hardy K, Wilson RP, Gillis CC, Tükel Ç, Koh AY, Burstein E, Hooper LV, Bäumler AJ, Winter SE. Precision editing of the gut microbiota ameliorates colitis. Nature. 2018 Dec 11;553(553). 208-211. NIHMSID: NIHMS938451.
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Miyata N, Morris LL, Chen Q, Thorne C, Singla A, Zhu W, Winter M, Melton SD, Li H, Sifuentes-Dominguez L, Llano E, Huff-Hardy K, Starokadomskyy P, Lopez A, Reese TA, Turer E, Billadeau DD, Winter SE, Burstein E. Microbial Sensing by Intestinal Myeloid Cells Controls Carcinogenesis and Epithelial Differentiation. Cell reports. 2018 Dec;24(24). 2342-2355. NIHMSID: NIHMS1505975.
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Gillis CC, Hughes ER, Spiga L, Winter MG, Zhu W, Furtado de Carvalho T, Chanin RB, Behrendt CL, Hooper LV, Santos RL, Winter SE. Dysbiosis-Associated Change in Host Metabolism Generates Lactate to Support Salmonella Growth. Cell host & microbe. 2018 Jan 10;23(23). 54-64.e6. NIHMSID: NIHMS921720.
2017
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Liu Y, Zhu W, Tan Y, Nakayasu ES, Staiger CJ, Luo ZQ. A Legionella Effector Disrupts Host Cytoskeletal Structure by Cleaving Actin. PLoS pathogens. 2017 Dec;13(13). e1006186.
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Spiga L, Winter MG, Furtado de Carvalho T, Zhu W, Hughes ER, Gillis CC, Behrendt CL, Kim J, Chessa D, Andrews-Polymenis HL, Beiting DP, Santos RL, Hooper LV, Winter SE. An Oxidative Central Metabolism Enables Salmonella to Utilize Microbiota-Derived Succinate. Cell host & microbe. 2017 Sep 13;22(22). 291-301.e6. NIHMSID: NIHMS898101.
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Hughes ER, Winter MG, Duerkop BA, Spiga L, Furtado de Carvalho T, Zhu W, Gillis CC, Büttner L, Smoot MP, Behrendt CL, Cherry S, Santos RL, Hooper LV, Winter SE. Microbial Respiration and Formate Oxidation as Metabolic Signatures of Inflammation-Associated Dysbiosis. Cell host & microbe. 2017 Feb 8;21(21). 208-219. NIHMSID: NIHMS842902.
2016
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Zhu W, Luo ZQ. Cell biology and immunology lessons taught by Legionella pneumophila. Science China. Life sciences. 2016 Jan;59(59). 3-10.
2015
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Wang T, Si M, Song Y, Zhu W, Gao F, Wang Y, Zhang L, Zhang W, Wei G, Luo ZQ, Shen X. Type VI Secretion System Transports Zn2+ to Combat Multiple Stresses and Host Immunity. PLoS pathogens. 2015 Jul;11(11). e1005020.
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Zhu W, Tao L, Quick ML, Joyce JA, Qu JM, Luo ZQ. Sensing cytosolic RpsL by macrophages induces lysosomal cell death and termination of bacterial infection. PLoS pathogens. 2015 Mar;11(11). e1004704.
2013
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Zhu W, Hammad LA, Hsu F, Mao Y, Luo ZQ. Induction of caspase 3 activation by multiple Legionella pneumophila Dot/Icm substrates. Cellular microbiology. 2013 Nov;15(15). 1783-95. NIHMSID: NIHMS495089.
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Tao L, Zhu W, Hu BJ, Qu JM, Luo ZQ. Induction of rapid cell death by an environmental isolate of Legionella pneumophila in mouse macrophages. Infection and immunity. 2013 Sep;81(81). 3077-88.
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Zhu W, Luo ZQ. Methods for determining protein translocation by the Legionella pneumophila Dot/Icm type IV secretion system. Methods in molecular biology (Clifton, N.J.). 954(954). 323-32.
2012
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Hsu F, Zhu W, Brennan L, Tao L, Luo ZQ, Mao Y. Structural basis for substrate recognition by a unique Legionella phosphoinositide phosphatase. Proceedings of the National Academy of Sciences of the United States of America. 2012 Aug 21;109(109). 13567-72.
2011
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Zhu W, Banga S, Tan Y, Zheng C, Stephenson R, Gately J, Luo ZQ. Comprehensive identification of protein substrates of the Dot/Icm type IV transporter of Legionella pneumophila. PloS one. 2011 Mar 9;6(6). e17638.
2009
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Zhu WH, Luo L, Wang JY, Zhuang XH, Zhong L, Liao K, Zeng Y, Lu YJ. Complete nucleotide sequence of pCTX-M360, an intermediate plasmid between pEL60 and pCTX-M3, from a multidrug-resistant Klebsiella pneumoniae strain isolated in China. Antimicrobial agents and chemotherapy. 2009 Dec;53(53). 5291-3.
2008
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Du L, Su Y, Sun D, Zhu W, Wang J, Zhuang X, Zhou S, Lu Y. Formic acid induces Yca1p-independent apoptosis-like cell death in the yeast Saccharomyces cerevisiae. FEMS yeast research. 2008 Jun;8(8). 531-9.
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Spiga L., Fansler R.T., Grote A., Langford-Butler M., Miller A.K., Neal M., Hale O.F., Wu Y., Singla D., Calcutt WADE, Rose A.E., Bresson M.M, Schrimpe-Rutledge A.C., Berdy B., Codreanu S.G., Washington M.K., Bratton B.P, Sherrod S.D., McLean J.A., Zengler K., Sears C.L, Behringer M.G., Gnirke A., Livny J., Olivares-Villagómez D., Earl A.M., Zhu W.. An Anaerobic Pathogen Rewires Host Metabolism to Fuel Oxidative Growth in the Inflamed Gut BioRxiv.