The finding that obesity, diabetes, and cardiovascular diseases are driven by inflammation and that metabolic pathways influence immune cell differentiation an function has led to the field of Immunometabolism. This new field seeks to understand links between metabolism and inflammation. Working with the Vanderbilt Diabetes Research and Training Center (VDRTC), VCI member study how metabolic pathways contribute to the pathogenesis of the Metabolic Syndrome and how metabolic pathways modulate immunity.
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Mark Boothby, M.D., Ph.D.Professor of Pathology, Microbiology and Immunology Professor of Medicine Signal transduction, transcription regulation mechanisms
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Mariana Xavier Byndloss, D.V.M., Ph.D.Assistant Professor of Pathology, Microbiology and Immunology Linking gut microbiota, host metabolism, and disease
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Sung Hoon Cho, Ph.D.Research Assistant Professor of Pathology, Microbiology and Immunology Immune response, cellular metabolism & tumor progression
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Wonder P. Drake, M.D.Professor of Medicine Director, Sarcoidosis Center of Excellence Molecular biology and immunopathogenesis of chronic inflammatory states, particularly sarcoidosis
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Todd D. Giorgio, Ph.D.Professor of Biomedical Engineering Professor of Chemical and Biomolecular Engineering Professor of Cancer Biology Protease-responsive biosensors for siRNA and drug delivery in vitro and in vivo
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Alyssa H. Hasty, Ph.D.Cornelius Vanderbilt Chair in Molecular Physiology and Biophysics Mechanisms by which obesity increases risk for disease
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Jonathan M. Irish, Ph.D.Assistant Professor of Cell & Developmental Biology Assistant Professor of Pathology, Microbiology and Immunology Cancer, precision medicine, computational biology, machine learning, cell signaling, chemical biology, single cell tools
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Meena S. Madhur, M.D., Ph.D.Assistant Professor of Medicine Assistant Professor of Molecular Physiology and Biophysics The role of T cells and T cell-derived cytokines in hypertension and renal/vascular dysfunction
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Amy S. Major, Ph.D.Associate Professor of Medicine Associate Professor of Pathology, Microbiology and Immunology Immunological mechanisms of autoimmunity in atherosclerosis
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Simon A. Mallal, M.B.B.S.Professor of Medicine Major E.B. Stahlman Chair in Infectious Diseases and Inflammation Professor of Pathology, Microbiology and Immunology Immunometabolism & Metabolic Diseases, Tumor Biology & Tumor Immunology
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Daniel J. Moore, M.D., Ph.D.Assistant Professor of Pediatrics Assistant Professor of Pathology, Microbiology and Immunology Immune regulation in autoimmunity and transplantation
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Dawn C. Newcomb, Ph.D.Assistant Professor of Medicine Assistant Professor of Pathology, Microbiology and Immunology Estrogen, testosterone, sex hormones, T cells, innate lymphoid cells, asthma, allergy
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Dolly Padovani- Claudio, M.D., Ph.D.Assistant Professor of Ophthalmology and Visual Sciences Vascular diseases of the retina
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Heather Pua, M.D., Ph.D.Assistant Professor of Pathology, Microbiology and Immunology Lung, miRNA, exRNA (extracellular RNA), extracellular vesicles, allergy, asthma, Th2
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Jeffrey C. Rathmell, Ph.D.Director, Vanderbilt Center for Immunobiology Professor of Pathology, Microbiology and Immunology Professor of Molecular Physiology & Biophysics Cornelius Vanderbilt Chair in Immunobiology T cell metabolism in inflammation and anti-tumor immunity
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Cynthia Reinhart-King, Ph.D.Cornelius Vanderbilt Professor of Engineering Professor of Biomedical Engineering Mechanisms driving tissue formation and disruption during atherosclerosis and cancer
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C. Henrique Serezani, Ph.D.Assistant Professor of Medicine, Infectious Disease Assistant Professor of Pathology, Microbiology and Immunology Understanding host defense in pre-existing inflammatory conditions
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Anil Shanker, Ph.D.Professor of Pathology, Microbiology and Immunology Cornelius Vanderbilt Chair in Pathology, Microbiology and Immunology Biochemistry and molecular biology of HIV infection; Antiviral mechanisms
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Edward R. Sherwood, Ph.D., M.D.Corneilius Vanderbilt Chair in Anesthesiology Professor of Anesthesiology Professor of Pathology, Microbiology and Immunology Mechanisms of sepsis-induced systemic inflammation and organ injury with emphasis on the roles of natural killer (NK) and T lymphocytes
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Luc Van Kaer, Ph.D.Elizabeth and John Shapiro Chair Professor of Pathology, Microbiology and Immunology Role of innate-type regulatory lymphocytes in health and chronic inflammatory diseases
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Nicole L. Ward, Ph.D.Vice Chair for Research, Department of Dermatology Professor of Dermatology Professor of Pathology, Microbiology and Immunology Dr. Ward's research interests include psoriasis, psoriatic arthritis (PsA), osteogenesis imperfecta (OI), lupus, hidradenitis suppurativa (HS), other inflammatory skin diseases, multi-‘omics, microbiome, and skin disease co-morbidities.
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John T. Wilson, Ph.D.Assistant Professor, Chemical & Biomolecular Enginering Assistant Professor, Biomedical Engineering Polymer science, nanotechnology, immunobiology, colloid and surface engineering, cell engineering, and drug delivery
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Keith T. Wilson, M.D.Thomas F. Frist Sr. Chair in Medicine Professor of Medicine Professor of Pathology, Microbiology and Immunology Host immune response to the gastric pathogen Helicobacter pylori
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Lan Wu, M.D.Research Associate Professor of Pathology, Microbiology and Immunology Interactions between the immune and metabolic systems, whole body metabolism
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Fiona E. Yull, D.Phil.Associate Professor of Cancer Biology Associate Professor of Pharmacology Ovarian, breast and lung cancer
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Sandra S. Zinkel, Ph.D., M.D.Associate Professor of Medicine Associate Professor of Cancer Biology Mechanisms by which normal and malignant cells regulate programed cell death or apoptosis following DNA damage
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