Immunometabolism and Metabolic Diseases Researchers

The finding that obesity, diabetes, and cardiovascular diseases are driven by inflammation and that metabolic pathways influence immune cell differentiation an function has led to the field of Immunometabolism.  This new field seeks to understand links between metabolism and inflammation.  Working with the Vanderbilt Diabetes Research and Training Center (VDRTC), VCI member study how metabolic pathways contribute to the pathogenesis of the Metabolic Syndrome and how metabolic pathways modulate immunity.

Mark Boothby, M.D., Ph.D

Mark Boothby, M.D., Ph.D.

Professor of Pathology, Microbiology and Immunology

Professor of Medicine

Signal transduction, transcription regulation mechanisms

 

Mariana Xavier Byndloss, D.V.M, Ph.D.

Mariana Xavier Byndloss, D.V.M., Ph.D.

Assistant Professor of Pathology, Microbiology and Immunology

Linking gut microbiota, host metabolism, and disease

 

Sung Hoon Cho, Ph.D.

Sung Hoon Cho, Ph.D.

Research Assistant Professor of Pathology, Microbiology and Immunology

Immune response, cellular metabolism & tumor progression

 

Wonder P. Drake, M.D.

Wonder P. Drake, M.D.

Professor of Medicine

Director, Sarcoidosis Center of Excellence

Molecular biology and immunopathogenesis of chronic inflammatory states, particularly sarcoidosis

 

Todd D. Giorgio, Ph.D.

Todd D. Giorgio, Ph.D.

Professor of Biomedical Engineering

Professor of Chemical and Biomolecular Engineering

Professor of Cancer Biology

Protease-responsive biosensors for siRNA and drug delivery in vitro and in vivo

 

Alyssa H. Hasty, Ph.D.

Alyssa H. Hasty, Ph.D.

Cornelius Vanderbilt Chair in Molecular Physiology and Biophysics

Mechanisms by which obesity increases risk for disease

 

Jonathan M. Irish, Ph.D.

Jonathan M. Irish, Ph.D.

Assistant Professor of Cell & Developmental Biology

Assistant Professor of Pathology, Microbiology and Immunology

Cancer, precision medicine, computational biology, machine learning, cell signaling, chemical biology, single cell tools

 

Meena S. Madhur, M.D., Ph.D.

Meena S. Madhur, M.D., Ph.D.

Assistant Professor of Medicine

Assistant Professor of Molecular Physiology and Biophysics

The role of T cells and T cell-derived cytokines in hypertension and renal/vascular dysfunction

 

Amy S. Major, Ph.D.

Amy S. Major, Ph.D.

Associate Professor of Medicine

Associate Professor of Pathology, Microbiology and Immunology

Immunological mechanisms of autoimmunity in atherosclerosis

 

Simon A. Mallal, M.B.B.S.

Simon A. Mallal, M.B.B.S.

Professor of Medicine

Major E.B. Stahlman Chair in Infectious Diseases and Inflammation

Professor of Pathology, Microbiology and Immunology

Immunometabolism & Metabolic Diseases, Tumor Biology & Tumor Immunology

 

Daniel J. Moore, M.D., Ph.D.

Daniel J. Moore, M.D., Ph.D.

Assistant Professor of Pediatrics

Assistant Professor of Pathology, Microbiology and Immunology

Immune regulation in autoimmunity and transplantation

 

Dawn C. Newcomb, Ph.D.

Dawn C. Newcomb, Ph.D.

Assistant Professor of Medicine

Assistant Professor of Pathology, Microbiology and Immunology

Estrogen, testosterone, sex hormones, T cells, innate lymphoid cells, asthma, allergy

 

Dolly Padovani- Claudio, M.D., Ph.D.

Dolly Padovani- Claudio, M.D., Ph.D.

Assistant Professor of Ophthalmology and Visual Sciences

Vascular diseases of the retina

 

Heather Pua, M.D., Ph.D.

Heather Pua, M.D., Ph.D.

Assistant Professor of Pathology, Microbiology and Immunology

Lung, miRNA, exRNA (extracellular RNA), extracellular vesicles, allergy, asthma, Th2

 

Jeffrey C. Rathmell, Ph.D.

Jeffrey C. Rathmell, Ph.D.

Director, Vanderbilt Center for Immunobiology

Professor of Pathology, Microbiology and Immunology

Professor of Molecular Physiology & Biophysics

Cornelius Vanderbilt Chair in Immunobiology

T cell metabolism in inflammation and anti-tumor immunity

 

Cynthia Reinhart-King, Ph.D.

Cynthia Reinhart-King, Ph.D.

Cornelius Vanderbilt Professor of Engineering

Professor of Biomedical Engineering

Mechanisms driving tissue formation and disruption during atherosclerosis and cancer

 

C. Henrique Serezani, Ph.D.

C. Henrique Serezani, Ph.D.

Assistant Professor of Medicine, Infectious Disease

Assistant Professor of Pathology, Microbiology and Immunology

Understanding host defense in pre-existing inflammatory conditions

 

Anil Shanker, Ph.D.

Anil Shanker, Ph.D.

Professor of Pathology, Microbiology and Immunology

Cornelius Vanderbilt Chair in Pathology, Microbiology and Immunology

Biochemistry and molecular biology of HIV infection; Antiviral mechanisms

 

Edward R. Sherwood, M.D., Ph.D.

Edward R. Sherwood, Ph.D., M.D.

Corneilius Vanderbilt Chair in Anesthesiology

Professor of Anesthesiology

Professor of Pathology, Microbiology and Immunology

Mechanisms of sepsis-induced systemic inflammation and organ injury with emphasis on the roles of natural killer (NK) and T lymphocytes

 

Luc Van Kaer, Ph.D.

Luc Van Kaer, Ph.D.

Elizabeth and John Shapiro Chair

Professor of Pathology, Microbiology and Immunology

Role of innate-type regulatory lymphocytes in health and chronic inflammatory diseases

 

John T. Wilson, Ph.D.

John T. Wilson, Ph.D.

Assistant Professor, Chemical & Biomolecular Enginering

Assistant Professor, Biomedical Engineering

Polymer science, nanotechnology, immunobiology, colloid and surface engineering, cell engineering, and drug delivery

 

Keith T. Wilson, M.D.

Keith T. Wilson, M.D.

Thomas F. Frist Sr. Chair in Medicine

Professor of Medicine

Professor of Pathology, Microbiology and Immunology

Host immune response to the gastric pathogen Helicobacter pylori

 

Lan Wu, M.D.

Lan Wu, M.D.

Research Associate Professor of Pathology, Microbiology and Immunology

Interactions between the immune and metabolic systems, whole body metabolism

 

Fiona E. Yull, D.Phil.

Fiona E. Yull, D.Phil.

Associate Professor of Cancer Biology

Associate Professor of Pharmacology

Ovarian, breast and lung cancer

 

Sandra S. Zinkel, M.D., Ph.D.

Sandra S. Zinkel, Ph.D., M.D.

Associate Professor of Medicine

Associate Professor of Cancer Biology

Mechanisms by which normal and malignant cells regulate programed cell death or apoptosis following DNA damage

 

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