Autoimmunity and Inflammation Researchers

The immune system must balance the maintenance of a capacity to eliminate an infinite array of pathogens with the necessity to not induce an immune response against oneself.  Insufficient or excessive immune responses can lead to immune deficiencies, autoimmunity, or inflammatory syndromes.  VCI members are exploring the cellular and genetic basis for these immune dysregulation disorders to better understand basic immunology and mechanisms of inflammation.

Holly Algood, Ph.D.

Holly Algood, Ph.D.

Associate Professor of Pathology, Microbiology and Immunology

Assistant Professor of Medicine

Immune response to Helicobacter pylori

 

Manuel Ascano, Ph.D.

Manuel Ascano, PhD

Assistant Professor of Biochemistry

Assistant Professor of Pathology, Microbiology and Immunology

Post-transcriptional gene regulation in innate immunity and cellular stress

 

Thomas M. Aune, Ph.D.

Thomas M. Aune, Ph.D.

Professor of Medicine

Associate Professor of Pathology, Microbiology and Immunology

Functional genomic and epigenetic approaches to understanding gene regulation

 

Justin M. Balko, Pharm D., Ph.D.

Justin M. Balko, Pharm D.,PhD.

Assistant Professor of Medicine

Assistant Professor of Pathology, Microbiology and Immunology

Translational cancer research focused on molecular therapeutics, onco-immunology & bioinformatics

 

Alexander Bick,MD, PhD

Alexander Bick, MD, PhD

Assistant Professor, Genetic Medicine

 

Leslie J. Crofford, M.D.

Leslie J. Crofford, M.D.

Professor of Medicine

Professor of Pathology, Microbiology and Immunology

Director, Division of Rheumatology & Immunology

Wilson Family Chair in Medicine

Innate and acquired immunity in inflammatory arthritis, myositis, scleroderma, fibromyalgia, pain

 

Craig L. Duvall, Ph.D.

Craig L. Duvall , Ph.D.

Professor of Biomedical Engineering

Rrug and nanoparticle targeting, intracellular biomacromolecular delivery, and systems for controlled release of growth factors and other extracellular-acting molecules

 

P. Brent Ferrell, M.D.

P. Brent Ferrell, Jr., M.D.

Assistant Professor of Medicine

Molecular investigations in myeloid disease

 

Todd D. Giorgio, Ph.D.

Todd D. Giorgio, Ph.D.

Professor of Biomedical Engineering

Professor of Chemical and Biomolecular Engineering

Professor of Cancer Biology

Protease-responsive biosensors for siRNA and drug delivery in vitro and in vivo

 

Jeremy A. Goettel, Ph.D.

Jeremy A. Goettel, Ph.D.

Assistant Professor of Medicine

Assistant Professor of Pathology, Microbiology and Immunology

Mechanisms regulating intestinal immunity

 

Jonathan M. Irish, Ph.D.

Jonathan M. Irish, Ph.D.

Assistant Professor of Cell & Developmental Biology

Assistant Professor of Pathology, Microbiology and Immunology

Cancer, precision medicine, computational biology, machine learning, cell signaling, chemical biology, single cell tools

 

John Joseph Karijolich, Ph.D.

John Joseph Karijolich, Ph.D.

Associate Professor of Pathology, Microbiology and Immunology

Oncogenic Viruses, RNA-based mechanisms of antiviral and antitumor immunity, epigenomics, CRISPR screens

 

Ken Lau, Ph.D.

Ken Lau, Ph.D.

Associate Professor of Cell and Developmental Biology

Single-cell, computational systems biology, inflammation, colorectal cancer, stem cells, epithelial biology, cell state specification, signal transduction

 

Andrew J. Link, Ph.D.

Andrew J. Link, Ph.D.

Associate Professor of Pathology, Microbiology and Immunology

Associate Professor of Chemistry

Assistant Professor of Biochemistry

Functional genomics and systems biology analysis of the immune response and translation

 

Meena S. Madhur, M.D., Ph.D.

Meena S. Madhur, M.D., Ph.D.

Assistant Professor of Medicine

Assistant Professor of Molecular Physiology and Biophysics

The role of T cells and T cell-derived cytokines in hypertension and renal/vascular dysfunction

 

Amy S. Major, Ph.D.

Amy S. Major, Ph.D.

Associate Professor of Medicine

Associate Professor of Pathology, Microbiology and Immunology

Immunological mechanisms of autoimmunity in atherosclerosis

 

Simon A. Mallal, MBBS

Simon A. Mallal, M.B.B.S.

Professor of Medicine

Major E.B. Stahlman Chair in Infectious Diseases and Inflammation

Professor of Pathology, Microbiology and Immunology

Immunometabolism & Metabolic Diseases, Tumor Biology & Tumor Immunology

 

Janet Markle

Janet Markle, Ph.D.

Assistant Professor of Pathology, Microbiology and Immunology

Inborn errors of immunity, Molecular and cellular immunology, pediatric immune-mediated diseases

 

Daniel J. Moore, MD, PhD

Daniel J. Moore, Ph.D., M.D.

Assistant Professor of Pediatrics

Assistant Professor of Pathology, Microbiology and Immunology

Immune regulation in autoimmunity and transplantation

 

Danyvid Olivares-Villagomez, PhD

Danyvid Olivares-Villagomez, Ph.D.

Assistant Professor of Pathology, Microbiology and Immunology

Mucosal immunology, IEL, iCD8alpha, osteopontin, granzyme

 

Dolly Padovani-Claudio, MD, PhD

Dolly Padovani- Claudio, M.D., Ph.D.

Assistant Professor of Ophthalmology and Visual Sciences

Vascular diseases of the retina

 

Anna Patrick, MD, PhD

Anna Patrick, M.D., Ph.D.

Pediatric Rheumatology

Assistant Professor, Department of Pediatrics

Mary Philip, MD, PhD

Mary Philip, M.D., Ph.D.

Assistant Professor of Medicine

Assistant Professor of Pathology, Microbiology and Immunology

Hematology, Cancer Immunology, T cells, Epigenetics, Autoimmunity, Differentiation

 

Heather Pua, MD, PhD

Heather Pua, M.D.,Ph.D.

Assistant Professor of Pathology, Microbiology and Immunology

Lung, miRNA, exRNA (extracellular RNA), extracellular vesicles, allergy, asthma, Th2

 

Jeffery C. Rathmell, PhD

Jeffery C. Rathmell, Ph.D.

Director, Vanderbilt Center for Immunobiology

Professor of Pathology, Microbiology and Immunology

Professor of Molecular Physiology & Biophysics

Cornelius Vanderbilt Chair in Immunobiology

T cell metabolism in inflammation and anti-tumor immunity

 

Michael Savona, MD

Michael Savona, MD

Acting Chief, Hematology, Cellular Therapy and Stem Cell Transplantation;

Professor of Medicine

 

Ana P. Serezani, PhD.

Ana P. Serezani, Ph.D.

Research Assistant Professor of Medicine

Immunology, Inflammation, T cells, lung remodeling and fibrosis.

 

C. Henrique Serezani, PhD

C. Henrique Serezani, Ph.D.

Assistant Professor of Medicine, Infectious Disease

Assistant Professor of Pathology, Microbiology and Immunology

Understanding host defense in pre-existing inflammatory conditions

 

Chase Spurlock, Ph.D.

Charles C. Spurlock III, Ph.D.

Research Instructor in Medicine

Professor of Pathology, Microbiology and Immunology

Long non-coding RNAs, autoimmune disease, RNA biology, RNA sequencing, adaptive immune system, T cells, gene regulation

 

 

Eric Skaar, PhD, MPH

Eric P. Skaar, Ph.D., M.P.H.

Director, Vanderbilt Institute for Infection, Immunology & Inflammation

Director, Division of Molecular Pathogenesis

Ernest W. Goodpasture Chair in Pathology

Vice Chair for Basic Research, Department of Pathology, Microbiology, and Immunology

Factors and processes involved in the battle for metal between bacterial pathogens and their hosts

 

James W. Thomas, MD

James W. Thomas, II, M.D.

Professor of Medicine

Professor of Pathology, Microbiology & Immunology

Mechanisms that regulate immune tolerance and why they fail in autoimmune disorders such at type 1 diabetes

 

Luc Van Kaer, Ph.D

Luc Van Kaer, Ph.D.

Elizabeth and John Shapiro Chair

Professor of Pathology, Microbiology and Immunology

Role of innate-type regulatory lymphocytes in health and chronic inflammatory diseases

 

John T. Wilson, PhD

John T. Wilson, Ph.D.

Assistant Professor, Chemical & Biomolecular Enginering

Assistant Professor, Biomedical Engineering

Polymer science, nanotechnology, immunobiology, colloid and surface engineering, cell engineering, and drug delivery

 

Keith Wilson, MD

Keith T. Wilson, M.D.

Thomas F. Frist Sr. Chair in Medicine

Professor of Medicine

Professor of Pathology, Microbiology and Immunology

Host immune response to the gastric pathogen Helicobacter pylori

 

Lan Wu, MD

Lan Wu, M.D.

Research Associate Professor of Pathology, Microbiology and Immunology

Interactions between the immune and metabolic systems, whole body metabolism

 

Fiona E. Yull, DPhil

Fiona E. Yull, D.Phil.

Associate Professor of Cancer Biology

Associate Professor of Pharmacology

Ovarian, breast and lung cancer

 

Matthew R. Alexander, Ph.D, M.D

Matthew R. Alexander, Ph.D, M.D

Assistant Professor of Medicine, Division of Clinical Pharmacology and Cardiovascular Medicine

 

Sandra Zinkel, MD, PhD

Sandra S. Zinkel, Ph.D., M.D

Associate Professor of Medicine

Associate Professor of Cancer Biology

Mechanisms by which normal and malignant cells regulate programed cell death or apoptosis following DNA damage

 

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