Results from the iAdhere trial conducted through the TB Trials Consortium have been published in the Annals of Internal Medicine. This randomized trial aimed to compare treatment completion and safety of once-weekly isoniazid and rifapentine by self-administration versus direct observation. Enrollment sites were located in the US, Spain, Hong Kong, and South Africa; Vanderbilt and the Metro Nashville Health Department participated in enrollment.

Congratulations to Graeme Meintjes at University of Cape Town on a newly funded D43 training grant from the Fogarty International Center (FIC) titled "HIV-Associated Tuberculosis Training Program (HATTP)". VUMC is excited to be a US partner site for this training grant, along with Johns Hopkins University.

Charles L. Daley, MD, Chief of the Division of Mycobacterial and Respiratory Infections at National Jewish Health in Denver, CO, presented Medicine Grand Rounds today. His talk was sponsored by the M. Glenn Koenig, Visiting Professorship in Infectious Diseases, hosted by the Division of Infectious Disease. During his talk, "Nontuberculous Mycobacteria: What's in a name?", he described the many species of mycobacteria and how they affect disease progression.

The Regional Prospective Observational Research for Tuberculosis (RePORT)- International Annual Meeting was held Tuesday, September 12 through Wednesday, September 13, 2017 in Rio de Janeiro, Brazil. RePORT-International is now composed of 5 regions: Brazil, China, India, Indonesia, and South Africa.

Chris Fiske, MD, MPH and Spyros Kalams, MD, presented at ID Grand Rounds on Thursday, September 7th. Dr. Fiske presented her work on the host immune response to M.tuberculosis, including a focus on patients with extrapulmonary tuberculosis. Dr. Kalams presented on the immunology of tuberculosis and an ongoing study funded by the NIH and CNPq in Brazil which is attempting to identify an immune signature that predicts active TB disease.