Wang J, Qian J, Hoeksema MD, Zou Y, Espinosa AV, Rahman SM, Zhang B, Massion PP. Integrative genomics analysis identifies candidate drivers at 3q26-29 amplicon in squamous cell carcinoma of the lung. Clinical cancer research : an official journal of the American Association for Cancer Research. 2013 Oct 15;19(19). 5580-90. PMID: 23908357 [PubMed] PMCID: PMC3807802 NIHMSID: NIHMS510860.
Chromosome 3q26-29 is a critical region of genomic amplification in lung squamous cell carcinomas (SCC). Identification of candidate drivers in this region could help uncover new mechanisms in the pathogenesis and potentially new targets in SCC of the lung.