Improving Lung Cancer Diagnosis with Computed Tomography Radiomics and Serum Histoplasmosis Testing.


Indeterminate pulmonary nodules (IPNs) are a diagnostic challenge in regions where pulmonary fungal disease and smoking prevalence are high. We aimed to determine the impact of a combined fungal and imaging biomarker approach compared to a validated prediction model (Mayo) to rule out benign disease and diagnose lung cancer.