Expression of focal adhesion kinase in small-cell lung carcinoma.

Ocak S, Chen H, Callison C, Gonzalez AL, Massion PP. Expression of focal adhesion kinase in small-cell lung carcinoma. Cancer. 2012 Mar 1;118(118). 1293-301. PMID: 21800286 [PubMed] PMCID: PMC3673887 NIHMSID: NIHMS471845.

Abstract

The focal adhesion kinase (FAK) is a non-receptor tyrosine kinase linked to tumor growth, invasion, and metastasis. FAK is overexpressed and associated with prognosis in many cancers, but its prognostic value in small-cell lung carcinoma (SCLC) is unknown and was the focus of this study.