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Hostetter L, Brown LM, Rajagopalan S, Dulohery-Scrodin MM, Edell ES, Lester MG, Maldonado F, Lentz R, Bartholmai BJ, Peikert T. Bronchoscopic lung volume reduction: model for assisted target lobe selection. BMJ open respiratory research. 2025 Jun 4;12(12).
Abstract
Bronchoscopic lung volume reduction with endobronchial valves (EBV) is an effective procedure for patient with severe emphysema to improve lung function, exercise tolerance, dyspnoea and quality of life. Optimisation of patient and treatment lobe selection is essential for successful EBV outcomes. While clinical selection criteria are rigorous, many centres use a multidisciplinary team and rely on previous clinical experience for the selection process. To aid objective clinical decision making, we present a mathematical model to facilitate patient and target lobe selection.