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Marmor HN, Deppen SA, Welty V, Kammer MN, Godfrey CM, Patel K, Maldonado F, Chen H, Starnes SL, Wilson DO, Billatos E, Grogan EL. Improving Lung Cancer Diagnosis with Computed Tomography Radiomics and Serum Histoplasmosis Testing. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 2022 Dec 16.
Abstract
Indeterminate pulmonary nodules (IPNs) are a diagnostic challenge in regions where pulmonary fungal disease and smoking prevalence are high. We aimed to determine the impact of a combined fungal and imaging biomarker approach compared to a validated prediction model (Mayo) to rule out benign disease and diagnose lung cancer.