Rathmell JC. T cell Myc-tabolism. Immunity. 2011 Dec 23;35(35). 845-6. PMID: 22195738 [PubMed] PMCID: PMC3267318 NIHMSID: NIHMS350985.
T cell activation leads to a dramatic demand for energy and biosynthetic precursors that is met by increased glucose and glutamine metabolism. In this issue of Immunity, Wang et al. (2011) show that Myc is essential in T cell metabolic reprogramming.