C. Buddy Creech, MD, MPH

Director, Vanderbilt Vaccine Research Program
Associate Professor of Pediatrics
Division of Pediatric Infectious Diseases

C. Buddy Creech, MD, MPH, FPIDS is Associate Professor of Pediatrics, Division of Pediatric Infectious Diseases, at the Vanderbilt University School of Medicine in Nashville, Tennessee. He serves as Director of the Vanderbilt Vaccine Research Program, Principal Investigator of the NIH-funded Vanderbilt Vaccine and Treatment Evaluation Unit, and Co-Principal Investigator of the CDC-sponsored Clinical Immunization Safety Assessment Network. Dr. Creech’s research interests focus on the development and evaluation of new vaccines and therapeutics, particularly vaccines targeting influenza, pertussis, and S. aureus. His work combines innovative clinical trial design and next-generation immunologic assays to characterize the human response to infection and disease. He is currently leading COVID-related clinical trials at VUMC, including the evaluation of novel treatment options for hospitalized patients with COVID and trials of candidate SARS-CoV-2 vaccines.

Dr. Creech received a Bachelor of Science degree in Biology, cum laude, from Vanderbilt University prior to graduating with high honors from the University of Tennessee College of Medicine in Memphis, TN. He completed pediatric training at Vanderbilt Children’s Hospital, serving as Chief Resident in 2002. During fellowship in pediatric infectious diseases at Vanderbilt, he trained with Dr. Kathryn Edwards and received a master’s degree in public health. He is active in the Infectious Diseases Society of America (IDSA) and the Pediatric Infectious Diseases Society (PIDS), where he serves as President-Elect.