Contract Solicitation: Mycobacterium tuberculosis (MTB) Quality Assessment Program (TBQA)

The purpose of the proposed contract will be to provide a Mycobacterium tuberculosis (MTB) Quality Assessment Program (TBQA), a resource to: (1) support the ability of laboratories (Labs) to reliably perform study-specified MTB tests; (2) evaluate MTB technologies and specimen processes for use in clinical investigations; and (3) disseminate technical and scientific data. Notice ID: 75N93022R00015

Leonardo Barreto's work in the Sterling Lab investigating MIC in Mtb isolates

Leonardo Barreto, Public Health Technologist at Instituto Nacional de Infectologia Evandro Chagas – FIOCRUZ, has spent the last 6 months in the Sterling Lab evaluating subtle changes in drug resistance (Minimum Inhibitory Concentration - MIC) in M. tuberculosis isolates from study participants from the NIH-funded project “Predictors of treatment toxicity, failure, and relapse in HIV-related tuberculosis” (R01AI120790).

Identifying Host Cell Death Pathway Targets for Host-Directed Therapies for Treatment of Mtb and Mtb/HIV Co-Infection (R01, Clinical Trial Not Allowed)

Open Date (Earliest Submission Date): November 07, 2022 Expiration Date: December 08, 2024 The purpose of this Funding Opportunity Announcement (FOA) is to support mechanistic studies on host cell death pathways and their effect on immune responses to Mycobacterium tuberculosis (Mtb) and Mtb/HIV co-infection to identify immune targets for development of host-directed therapies.

Jason Cummins, MPH

Jason
Cummins
Director
TB Elimination Program, Tennessee Department of Health
Jason.Cummins@tn.gov

TB Elimination Alliance Announces 2022-2023 Mini-Grant Program

The Tuberculosis (TB) Elimination Alliance (TEA) is offering Mini-Grants to organizations serving Asian American (AA), Native Hawaiian, and Pacific Islander (NH/PI) communities that are disproportionately impacted by latent TB infection (LTBI) and/or TB. Additional preference is given to organizations currently serving Asian/Asian American (A/AA) and NH/PI populations with an interest in expanding to non-US born Latino American, and US born African American communities.

Nancy Séraphin, MPH, PhD visits Vanderbilt TB Center

Nancy Séraphin, MPH, PhD, Research Assistant Professor in the Department of Medicine, Division of Infectious Diseases and Global Medicine (IDGM), and the Emerging Pathogens Institute (EPI) at the University of Florida visited VUMC between June 13th-15th. Her visit was highlighted by meetings with the TB Center team, collaborative discussions with researchers at VUMC, and the presentation of a guest lecture entitled: "The public health importance of Mycobacterium tuberculosis intra-host genetic variability”.

NIAID June 2022 Council-Approved Concepts

Concepts represent early planning stages for program announcements, requests for applications, notices of special interest, or solicitations for Council's input. Concepts reveal possible initiatives or give you ideas for an investigator-initiated application.   Analyzing Early Events in Tuberculosis (TB) and TB/HIV Infection To Identify Interventional Targets Request for Applications—proposed FY 2024 initiative