Publications & News

1.  Gaddy, J.A., Radin, J.N., Loh, J.T., Ilca, T.F.,  Kehl-Fie, T.E., Piazuelo, M.B., Delgado, A.G., Peek, R.M., Jr., Cover, T.L., Chazin, W.J., Skaar, E.P.  (2014). The host protein calprotectin modulates the Helicobacter pylori cag Type IV secretion system via zinc sequestration.  PLoS Pathogens. 10(10): e1004450. doi:10.1371/journal.ppat.1004450. 
2.  Haley, K.P., Blanz, E.J., Kirk, L.A., Gaddy, J.A. (2014).  Bacterial pathogenesis:  Using high resolution microscopy techniques to study host-pathogen interactions.  2014 Edition.  Microscopy:  advances in scientific research and education.  Formatex publishing, Badajos, Spain. 
3.  Johnson, E.J., Gaddy, J.A.*, Voss, B.J., Hennig, E.E., Cover, T.L.  (2014). Genes required for assembly of pili associated with the Helicobacter pylori cag type IV secretion system.  Infection and Immunity. In press.
4.   Granke, M., Coulmier, A., Uppuganti, S., Gaddy, J.A., Does, M.D., Nyman, J.S. (2014). Insights into reference point indentation involving human cortical bone: sensitivity to tissue anisotropy and mechanical behavior. Journal of the Mechanical Behavior of Biomedical Materials. In press.
5.   Haley, K.P., Blanz, E.J., Gaddy, J.A. (2014).  High resolution electron microscopy of the Helicobacter pylori Cag Type IV secretion system pili produced in varying conditions of iron availability.  J. Vis. Exp. In press.
6.  Voss, B.J., Gaddy, J.A., McDonald, W.H., Cover, T.L.  (2014). Analysis of surface-exposed outer membrane proteins in Helicobacter pylori.  J. Bacteriol.  196(13):2455-2471.
7.  Radin, J.N., González-Rivera, C., Frick-Cheng, A.E., Sheng, J., Gaddy, J.A., Rubin, D.H., Scott Algood, H.M., McClain, M.S., Cover, T.L.  (2014). Role of Connexin 43 in Helicobacter pylori VacA-induced cell death.  Infect. Immun.  82(1):423-32.
8.  McClain, M.S., Duncan, S.S., Gaddy, J.A., Cover, T.L. (2013). Control of gene expression in Helicobacter pylori using the Tet repressor.  J. Microbiol. Methods. 95(3):336-341.
9.  Parekh, V.V., Wu, L., Boyd, K.L., Williams, J.A., Gaddy, J.A., Olivares-Villagomez, D., Cover, T.L., Zong, W.X., Zhang, J., Van Kaer, L.  Impaired autophagy, defective T cell homeostasis, and a wasting syndrome in mice with a T cell-specific deletion of Vps34.  (2013). J. Immunol.  190(10): 5086-101.
10.  Gaddy, J.A., Radin, J.N., Loh, J.T., Zhang, F., Washington, M.K., Peek, R.M., Algood, H.M.S., Cover, T.L.  (2013). High dietary salt intake exacerbates Helicobacter pylori-induced gastric carcinogenesis.  Infection and Immunity.  81(6):2258-67.
11.  Radin, J.N., Gaddy, J.A.*, Gonzalez-Rivera, C., Loh, J.T., Algood, H.M.S., Cover, T.L.  (2013)  Flagellar localization of a Helicobacter pylori autotransporter protein.  MBio.  4(2):e00613-12.
12.  Barrozo, R.M., Cooke, C.L., Hansen, L.M., Lam, A.M., Gaddy, J.A., Johnson, E.M., Cariaga, T.A., Suarez, G., Peek, R.M., Cover, T.L., Solnick, J.V. (2013). Functional plasticity in the Type IV secretion system of Helicobacter pylori.  PLoS Pathogens.  9(2):e1003189. 
13.  Noto, J.M., Gaddy, J.A., Lee, J.Y., Piazuelo, M.B., Friedman, D.B., Colvin, D.C., Romero-Gallo, J., Suarez, G., Loh, J., Slaughter, J.C., Tan, S., Morgan, D.R., Wilson, K.T., Bravo, L.E., Correa, P., Cover, T.L., Amieva, M.R., Peek, R.M. Jr.  (2012). Iron deficiency accelerates Helicobacter pylori-induced carcinogenesis in rodents and humans.  J. Clin. Invest.  123(1):479-92.
14.  Nwugo, C.C., Arivett, B.A., Zimbler, D.L., Gaddy, J.A., Richards, A.M., Actis, L.A. (2012).  Effect of ethanol on differential protein production and expression of potential virulence functions in the opportunistic pathogen Acinetobacter baumannii.  PLoS One.  7(12): e51936.
15.  Johnson, E.M., Gaddy, J.A.*, Cover, T.L. (2012).  Alterations in Helicobacter pylori triggered by contact with gastric epithelial cells.  Frontiers in Cellular and Infection Microbiology. 2:17. 
16.  Gaddy, J.A., Arivett, B.A., McConnell, M.J., Lopez-Rojas, R., Pachon, J., Actis, L.A.  (2012)  Role of acinetobactin-mediated iron acquisition functions in the interaction of Acinetobacter baumannii strain ATCC 19606T with human lung epithelial cells, Galleria mellonella caterpillars and mice.  Infection and Immunity. 80(3):1015-24.
17.  Schaffer, C.L., Gaddy, J.A., Loh, J.T., Johnson, E.M., Hill, S., Hennig, E.E., McClain, M.S., McDonald, W.H., Cover, T.L. (2011) Helicobacter pylori exploits a unique repertoire of type IV secretion components for pilus assembly at the bacteria-host cell interface.  PLoS Pathogens. 7(9):e1002237.
18.  Nwugo, C.C., Gaddy, J.A., Zimbler, D.L., Actis, L.A.  (2011) Deciphering the iron response in Acinetobacter baumannii:  a proteomics approach.  Journal of Proteomics. 74 (1): 44-58.
19.  Mussi, M.A., Gaddy, J.A., Arivett, B.A., Viale, A., Rasia, R., Actis, L.A.  (2010) The opportunistic human pathogen Acinetobacter baumannii senses and responds to blue light.  Journal of Bacteriology.  192 (24): 6336-45.
20.  Gaddy, J.A., Tomaras, A.P., and Actis, L.A.  (2009). The Acinetobacter baumannii 19606 OmpA protein plays a role in biofilm formation on abiotic and biotic surfaces and in the interaction of this pathogen with eukaryotic cells.  Infection and Immunity.  77 (8): 3150-60. 
21.  Gaddy, J.A. and Actis, L.A.  (2009). Regulation of Acinetobacter baumannii biofilm formation.  Future Microbiology. 4 (3):  273-278. 
22.  Breij, A., Gaddy, J.A., Meer, J., Koning, R., Koster, A., Broek, P., Actis, L.A., Nibbering, P., Dijkshoorn, L.  (2009). CsuA/BABCDE-dependent pili are not involved in the adherence of Acinetobacter baumannii ATCC 19606T to human airway epithelial cells and there inflammatory response.  Research in Microbiology.  160 (3): 213-218.