Seth graduated from the University of Pennsylvania in 2013 with a B.A. in Biochemistry and History and a M.S. in Chemistry. Following graduation, Seth joined the lab of Dr. Scott Hensley at the University of Pennsylvania and studied human antibody responses to influenza A viruses and the viral evasion of pre-existing immunity. Seth defended his PhD in 2018. In the lab, Seth is continuing to study antibody responses against influenza with special interests in defining conserved sites on viral proteins that are targeted by human antibodies and identifying how prior exposure shapes human antibody responses against influenza viruses.