COVID-19 Monoclonal Antibody Treatment at Vanderbilt Health

Vanderbilt Health offers COVID-19 monoclonal antibody infusion as an early treatment for COVID-19. This treatment is used to prevent the infection from getting worse and keep people from needing to go into the hospital.

Treatment is by appointment only. 

What is a monoclonal antibody infusion?

An infusion is when you get medicines or fluids through a needle or catheter. In this case, the infusion contains proteins called monoclonal antibodies that help the body fight COVID-19.

So far, we have treated more than 1,000 patients with COVID-19 at high risk for going into the hospital. Of those, only about 4% have needed to go into the hospital. This compares about to about 9% of such patients who have not had COVID-19 monoclonal antibody treatment. 

The Food and Drug Administration has given 2 combinations of medicines an "emergency use authorization." This is when the FDA allows providers to use unapproved medicines during a public health emergency like the COVID-19 pandemic.

The infusions are:

Can I come to your clinic for a monoclonal antibody infusion?

You must have an appointment. And these things must be true:

  • You’ve tested positive for COVID-19, but you’re not in the hospital.
  • Your first signs of COVID-19 infection started 10 days ago or less.
  • You’re at least 18 years old and at risk of a severe COVID-19 infection that could put you in the hospital because:
    • You're 40 years old or older.
    • You're 18 to 39 years old and you:
    • have a medical problem that suppresses your immune system or you take immune-suppressing medicine.
    • have diabetes.
    • have kidney disease.
    • are overweight with a body mass index of 25 or higher.
    • have heart or lung disease.
    • are pregnant.

If you have any new or higher oxygen requirements because of COVID-19, an antibody infusion isn’t helpful and should not be given.

Can I have monoclonal antibody treatment if I have had a COVID-19 vaccine?

Yes, you can have this treatment.

If I have COVID-19 and want to get a monoclonal antibody infusion at your clinic, what should I do?

If you’re already a Vanderbilt Health patient, contact your provider through My Health at Vanderbilt or by phone. Ask them to refer you to the COVID-19 Monoclonal Antibody Infusion Clinic.

If you don’t have a regular Vanderbilt provider, go to a Vanderbilt Health Walk-in Clinic or make a Vanderbilt Health On-Call appointment. We can examine you and decide if you are medically stable to receive the infusion.

Monoclonal antibody infusion therapy is also available at Vanderbilt Wilson County Hospital. Talk with your primary care provider or call Vanderbilt Integrated Primary Care in Lebanon at (615) 444-1180.