The fields of infection biology, immunobiology and inflammation research is varied and ever-expanding. Researchers the world over are making discoveries that contribute greatly to our collective understanding of health and disease. VI4 is committed to providing our members, students, and community resources to aid in knowledge-building in these core VI4 research areas. Please check out our current curated recommended reading list below from scientists across the country!
Recommended Reading - March & April 2024
- Dopamine transients follow a striatal gradient of reward time horizons. Mohebi A, et al. in Nature Neuroscience, February 6, 2024
- Bacteriophage infection and killing of intracellular Mycobacterium abscessus. Schmalstig A, et al. in mBio, December 7, 2023
- ADAR1p150 prevents MDA5 and PKR activation via distinct mechanisms to avert fatal autoinflammation. Hu Shi-Bin, Et al. in Molecular Cell, November 2, 2023
- Long 3'UTRs predispose neurons to inflammation by promoting immunostimulatory double-stranded RNA formation. Dorrity T, et al. in Science Immunology, October 27, 2023
- Microbiota-derived butyrate restricts tuft cell differentiation via histone deacetylase 3 to modulate intestinal type 2 immunity. Eshleman E, et al. in Cell Immunity, February 1, 2024
Recommended Reading - January & February 2024
- Synthetic Glycans Reveal Determinants of Antibody Functional Efficacy against a Fungal Pathogen. Crawford C, et al. in ACS Infectious Diseases, October 19, 2023
- Emapalumab for the treatment of refractory cytokine release syndrome in pediatric patients. Schuelke M, et al. in Blood Advances, September 18, 2023
- Molecular jackhammers eradicate cancer cells by vibronic-driven action. Ayala-Orozco C, et al. in Nature Chemistry, December 19, 2023
- Kupffer cell–like syncytia replenish resident macrophage function in the fibrotic liver. Peiseler M, et al. in Science, September 9, 2023
- A geometry-based approach to make viable-cell counting easy and cheap. Meyer C, et al. in Nature Microbiology, November 22, 2023
Recommended Reading - December 17th, 2023
- Probiotic-guided CAR-T cells for solid tumor targeting. Vincent R, et al. in Science, October 12, 2023
- A Candida auris–specific adhesin, Scf1, governs surface association, colonization, and virulence. Santana D, et al. in Science, September 28, 2023
- E-selectin-mediated rapid NLRP3 inflammasome activation regulates S100A8/S100A9 release from neutrophils via transient gasdermin D pore formation. Peruenster M, et al. in Nature Immunology, October 30, 2023
- Selection of a de novo gene that can promote survival of Escherichia coli by modulating protein homeostasis pathways. Idan Frumkin & Michael T. Laub. in Nature Ecology & Evolution, November 9, 2023
- Discovery of antibiotics that selectively kill metabolically dormant bacteria. Zheng E, et al . in PNAS, November 28, 2023
Recommended Reading - November 19th, 2023
- Type I interferons and Mycobacterium tuberculosis whole cell lysate induce distinct transcriptional responses in M. tuberculosis infection. Mutua F, et al. in Tuberculosis, September 11, 2023
- Activation of AIM2 by hepatitis B virus results in antiviral immunity that suppresses hepatitis C virus during coinfection. Li Y, et al. in Journal of Virology, August 28, 2023
- Divergent Actions of Renal Tubular and Endothelial Type 1 IL-1 Receptor Signaling in Toxin-Induced AKI. Ren J, et al. in Journal of the American Society of Nephrology, October 1, 2023
- CD8 T cell tolerance results from eviction of immature autoreactive cells from the thymus. Badr M, et al. in Science, November 2, 2023
- Sialic acid plays a pivotal role in licensing Citrobacter rodentium’s transition from the intestinal lumen to a mucosal adherent niche. Liang Q, et al. in PNAS, July 3, 2023
Recommended Reading - October 8th, 2023
- ApoE isoform– and microbiota-dependent progression of neurodegeneration in a mouse model of tauopathy. Seo DO, et al. in Science, January 13, 2023
- Heteroresistance to cefepime– taniborbactam in metallo-β-lactamaseencoding Enterobacterales. Weiss D, et al. in The Lancet, July 5, 2023
- Effect of Micro-Patterned Mucin on Quinolone and Rhamnolipid Profiles of Mucoid Pseudomonas aeruginosa under Antibiotic Stress. Bohn, P W, et al. in ACS Infectious Diseases, December 13, 2022
- Systemic application of bone-targeting peptidoglycan hydrolases as a novel treatment approach for staphylococcal bone infection. Keller A, et al. in mBio, September 28, 2023
- Variant STAT4 and Response to Ruxolitinib in an Autoinflammatory Syndrome. Baghdassarian H, et al. in The New England Journal of Medicine, June 15, 2023
Recommended Reading - September 17th, 2023
- Phage diversity in cell-free DNA identifies bacterial pathogens in human sepsis cases. Haddock N, et al. in Nature Microbiology, June 12, 2023
- Biofilm formation on human immune cells is a multicellular predation strategy of Vibrio cholerae. Vidakovic L, et al. in Cell, May 8, 2023
- PD-1 maintains CD8 T cell tolerance towards cutaneous neoantigens. Damo M, et al. in Nature, June 21, 2023
- Individual bat virome analysis reveals co-infection and spillover among bats and virus zoonotic potential. Wang J, et al. in Nature Communications, July 10, 2023
- Influenza A virus coinfection dynamics are shaped by distinct virus-virus interactions within and between cells. Delima G, et al. in PLOS Pathogens, March 2, 2023
Recommended Reading - August 8th, 2023
- The enteric nervous system relays psychological stress to intestinal inflammation. Schneider K, et al. in Cell, May 5, 2023
- Viriforms—A New Category of Classifiable Virus-Derived Genetic Elements. Kuhn J & Koonin E. in Biomolecules, February 13, 2023
- De novo evolution of macroscopic multicellularity. Bozdag G. O, et al. in Nature, May 10, 2023
- Droplet Tn-Seq identifies the primary secretion mechanism for yersiniabactin in Yersinia pestis. Price, S, et al. in EMBO Reports, July 28, 2023
- Ectocytosis renders T cell receptor signaling self-limiting at the immune synapse. Stinchcombe J, et al. in Science, May 23, 2023
Recommended Reading - July 9th, 2023
- Multivalent human antibody-centyrin fusion protein to prevent and treat Staphylococcus aureus infections. Buckley, P et al. in Cell Host & Mircobe, May 10, 2023
- Neutrophil metabolomics in severe COVID-19 reveal GAPDH as a suppressor of neutrophil extracellular trap formation. Li Y, et al. in Nature Communications, May 5, 2023
- Age-induced alterations of granulopoiesis generate atypical neutrophils that aggravate stroke pathology . Gullotta G, et al. in Nature Immunology, May 15, 2023
- Infection leaves a genetic and functional mark on the gut population of a commensal bacterium. Tawk C, et al. in Cell Host & Microbe, May 10, 2023
- Mirusviruses link herpesviruses to giant viruses. Gaia M, et al. in Nature, April 19, 2023
Recommended Reading - June 4th, 2023
- Role of Caspases and Gasdermin A during HSV-1 Infection in Mice. Li L, et al. in Viruses, September 13, 2022
- S+C121:C124tunning of neutrophils accounts for the anti-inflammatory effects of clodronate liposomes. Culemann S, et al. in Journal of Experimental Medicine, March 28, 2023
- Profiling the human intestinal environment under physiological conditions. Shalon D, Et al. in Nature, May 10, 2023
- Exogenously Scavenged and Endogenously Synthesized Heme Are Differentially Utilized by Mycobacterium tuberculosis. Donegan R, et al. in Microbiology Spectrum, September 28, 2022
- Spatial transcriptome uncovers rich coordination of metabolism in E. coli K12 biofilm. Wang T, et al. in Nature Chemical Biology, April 13, 2023
Recommended Reading - May 8th, 2023
- Mitochondrial ROS promotes susceptibility to infection via gasdermin D-mediated necroptosis. Weindel C, et al. in Cell, August 18, 2022
- CTCF mediates CD8+ effector differentiation through dynamic redistribution and genomic reorganization. Liu J, et al. in Journal of Experimental Medicine, April 23, 2023
- Exploring Masses and Internal Mass Distributions of Single Carboxysomes in Free Solution Using Fluorescence and Interferometric Scattering in an Anti-Brownian Trap. Lavania A, et al. in The Journal of Physical Chemistry B, October 25, 2022
- STAT3 regulates CD8+ T cell differentiation and functions in cancer and acute infection. Sun Q, et al. in Journal of Experimental Medicine, April 3, 2023
- Neutrophil inflammasomes sense the subcellular delivery route of translocated bacterial effectors and toxins. Oh C, et al. in Cell Reports, November 22, 2022
