Current research in the Nicole Ward lab is focused on identifying the cellular and molecular mechanisms underlying inflammatory skin disease and its associated co-morbidities, including arthritis, CVD, IBD, and depression. We study skin and blood from mouse models and psoriasis patients using a Systems Biology approach with CyTOF, multi-colour FACs, RNASeq, ScSeq, and Spatial Seq in order to better understand how chronic inflammatory diseases are related.