My areas of interest are predictive modeling and model validation, missing data, diagnostic and prognostic research, health services research, cohort studies, clinical trials, cardiovascular disease, and reproducible research.
Dr. Harrell received his PhD in Biostatistics from the University of North Carolina in 1979. He was on the faculty of Duke University for 17 years and of the University of Virginia for 7 years. He founded the Division of Biostatistics and Epidemiology at the University of Virginia School of Medicine in 1996 and the Department of Biostatistics at Vanderbilt University in 2003. He has taught biostatistics and research methodology to hundreds of physicians since 1980 and has been a mentor or co-mentor to several physician investigators. He is an Associate Editor for Statistics in Medicine, a member of Faculty of 1000 Medicine, and a member of the policy advisory board for the Journal of Clinical Epidemiology. His specialties are development of accurate prognostic and diagnostic models, model validation, clinical trials, observational clinical research, technology evaluation, quantifying predictive accuracy, missing data imputation, clinical trials, pharmaceutical safety, flexible Bayesian design and analysis, and statistical graphics and reporting. He has worked on a large number of clinical trials.Dr. Harrell is a Fellow of the American Statistical Association and winner of its 2014 WJ Dixon Award for Excellence in Statistical Consulting. He was the 2008 Mitchell Lecturer for the Department of Statistics, Glasgow University. He is the 2012 Presidential Invited Lecturer for WNAR, International Biometric Society. He was an FDA expert consultant and a member of the NIH Biostatistical Methods and Research Design Study Section. He is the leader of the Design, Biostatistics, and Clinical Research Ethics program for the Vanderbilt NIH CTSA and is the director of the Statistics and Methodology Core for the Vanderbilt Kennedy Center for Research on Human Development. He is the PI of the NHLBI multinational ISCHEMIA trial DSMB statistical center. He is the author of the first and third most cited papers (on development of prognostic models) in the history of Statistics in Medicine and has 217 peer-reviewed publications (5 with >1000 citations).
- Akwo EA, Kabagambe EK, Wang TJ, Harrell FE, Blot WJ, Mumma M, Gupta DK, Lipworth L. Heart Failure Incidence and Mortality in the Southern Community Cohort Study. Circulation. Heart failure. 2017 Mar;10(3). PMID: 28255010 [PubMed]. PMCID: PMC5365148. NIHMSID: NIHMS851451.
- Ward MJ, Kripalani S, Zhu Y, Storrow AB, Wang TJ, Speroff T, Munoz D, Dittus RS, Harrell FE, Self WH. Role of Health Insurance Status in Interfacility Transfers of Patients With ST-Elevation Myocardial Infarction. The American journal of cardiology. 2016 Aug 1;118(3). 332-7. PMID: 27282834 [PubMed]. PMCID: PMC4949088. NIHMSID: NIHMS796790.