Publications

Chiusa M., Hu W., Liao H-J, Yan S., Borza C.M., de Caestecker M., Skrypnyk N.I., Fogo A.B., Donnert E., Pedchenko V., Li X., Zhang M-Z., Hudson B.G., Basak T., Vanacore R.M., Zent R., Pozzi A. (2019) “The extracellular matrix receptor discoidin domain receptor 1 regulates collagen transcription by translocating to the nucleus” Journal of the American Society of Nephrology

Geister, K., López-Jiménez, A., Houghtaling, S., Ho, O., Vanacore, R.M., and Beier, D. (2019) “Loss of Function of Colgalt1 disrupts Collagen Post-Translational Modification and Causes Musculoskeletal Defects” Disease Models and Mechanisms

#Merl-Pham, J., #Basak, T., Knüppel, L., Ramanujam, D., Behr,J., Engelhardtd, S., Eickelberg, O., Hauck, S., *Vanacore, R.M. and *Staab-Weijnitz, C.A. (2019) “Quantitative Proteomic Profiling of Extracellular Matrix and collagen post-translational modifications induced by transforming growth factor-β1 on the lung fibroblast”. Matrix Biology Plus 

Vanacore R.,Eskew J.D., Sung L., Davis T., Smith A. “Safe Coordinated Trafficking of Heme and Iron with Copper Maintain Cell Homeostasis: Modules from the Hemopexin System”. Review article in BioMetals April 17, 2019. DOI: 10.1007/s10534-019-00194-4. 

López-Jiménez A, Basak T, Vanacore RM (2017) Proteolytic Processing of Lysyl Oxidase like-2 in the Extracellular Matrix is Required for Crosslinking of Basement Membrane Collagen IV. J Biol Chem doi: 10.1074/jbc.M117.798603

Brown K., Cummings C., Vanacore R., Hudson BG (2017) Building Collagen IV Smart Scaffolds on the Outside of Cells. Prot Scie DOI: 10.1002/pro.3283

Añazco, A, López-Jiménez, A., Rafi, M., Vega-Montoto, L., Zhang, M-Z, Hudson, BG, and Vanacore, RM “Lysyl Oxidase Like-2 Crosslinks Collagen IV of Glomerular Basement Membrane”. J Biol Chem 291, 25999-26012.

Cummings C.F., Pedchenko V., Brown KL., Colon S, Rafi M., Jones-Paris, C., Pokydeshava, P., Liu, M., Pastor-Pareja, J., Stothers C., Ero-Tolliver IA., McCall A.S., Vanacore R.M., Bhave G., Santoro S., Blackwell T., Zent R., Pozzi A., and Hudson B.G. (2016) “Extracellular chloride signals collagen IV network assembly during basement membrane formation” The Journal of Cell Biology May 23;213(4):479-94

Choma, DP., Vanacore, RM., Naylor, H., Zimmerman, IA., Pavlichenko, A., Pavlichenko, A., Foye, L., Harris, RC., Dikov, MM., and Tchekneva, EE. (2016) “Association of a Single Nucleotide Polymorphism in the AQP11 Gene with Increased Risk for CKD Development in Patients with Type 2 Diabetes” American Journal of Renal Physiology 310(5):F416-25

Basak T., Vega-Montoto, L., Zimmerman, L., Tabb, D., Hudson, BG. and Vanacore, RM. (2015) “Mass Spectrometry Characterization of Postranslational hydroxylations and glycosylations of Collagen IV” Journal of Proteomics Research. 15(1): 245–58. PMID: 26593852 

Robertson WE, Rose KL, Hudson BG, Vanacore RM* (2014) “Supramolecular Organization of the a121-a565 Collagen IV Network” J. Biol. Chem. pii: jbc.M114.571844.

Chen X, Wang H, Liao H, Hu W, Gewin L, Mernaugh G, Zhang S, Zhang S-Y, Vega-Montoto L, Vanacore RM, Fässler R, Zent R, Pozzi A. (2014) “Integrin α1β1-mediated tyrosine dephosphorylation of the type II TGF-β receptor controls Smad-dependent pro-fibrotic signaling” The Journal of Clinical Investigation doi: 10.1172/JCI71668.

McCall AS*, Cummings CF*, Bhave G*, Vanacore RM, Page-McCaw A, and Hudson BG (2014) Bromine is an essential trace element for assembly of collagen IV scaffolds in tissue development and architecture. Cell 157(6):1380-92.

Fidler AL*, Vanacore RM*, Chetyrkin SV*, Pedchenko VK, Bhave G, Yin VP, Stothers CL, Rose KL, McDonald WH, Clark TA, Borza D-B, Steele RE, Ivy MT, the Aspirnauts, Hudson JK, and Hudson BG (2014) “A unique covalent bond in basement membrane is a primordial innovation for tissue evolution”. PNAS Jan 7; Vol. 111 (1) 331-6. Asterisk (*) denotes equal contribution to this work. Download PDF pdf-icon-transparent.gif

Steenhard BM, Vanacore RM, Friedman DB, Zelenchuk A, Stroganova, Isom K, St. John PL, Hudson BG, and Abrahamson D. (2012) “Upregulated Expression of Integrin α1 in Mesangial Cells and Integrin α3 and Vimentin in Podocytes of Col4a3-Null (Alport) Mice” PLOS ONE; Vol 7 (12), e50745. Download PDF pdf-icon-transparent.gif

*Bhave G., *Cummings CF, *Vanacore RM, Kumagai-Cresse C, Ero-Tolliver IA, Rafi M., Kang JS, Pedchenko VP, Fessler LI, Fessler JH., and Hudson BG (2012) “Peroxidasin Forms Sulfilimine Chemical Bonds Using Hypohalous Acids In Tissue Genesis” Nature Chemical Biology. Sep;8(9):784-90 Asterisk (*) denotes equal contribution to this work.  Download PDF pdf-icon-transparent.gif

*Vanacore R., Pedchenko V., Gautam B., and Hudson BG (2011) “Sulfilimine Crosslinks in Goodpasture’s Disease” Clinical and Experimental Immunology Clinical & Experimental Immunology Special Issue: 15th International Vasculitis and ANCA Workshop, Volume 164, Issue Supplement s1, pages 4–6. Asterisk (*) denotes corresponding author.  Download PDF pdf-icon-transparent.gif

Pedchenko V., Vanacore R., and Hudson BG. (2011)” Goodpasture’s Disease: molecular architecture of the autoantigen provides clues to etiology and pathogenesis” Current Opinion in Nephrology & Hypertension. 20(3):290-296.  Download PDF pdf-icon-transparent.gif

Pedchenko V., Bondar O., Fogo A.B., Vanacore R., Voziyan P., Kitching A. R., Wieslander J., Kashtan C., Borza D-B., Neilson E.G., Wilson C., and Hudson B. G. (2010) “Molecular architecture of the Goodpasture autoantigen in anti-GBM nephritis” N Engl J Med. Jul 22;363(4):343-54 Download PDF pdf-icon-transparent.gif

*Vanacore R., Ham A.J., Voehler M., Sanders C.R., Conrads T.P., Veenstra T., Sharpless K.B., Dawson P., *Hudson BG. (2009) “A Sulfilimine Bond Identified in Collagen IV” Science 325(5945), 1230-1234. Asterisk (*) denotes co-corresponding author. Download PDF pdf-icon-transparent.gif

Article recommended by Faculty of 1000 http://f1000biology.com/article/id/1163786/evaluation

Vanacore R.M., Ham A.J., Cartailler, JP., Sundaramoorthy M., Todd P., Pedchenko, V., Sado Y., Borza D.B., and Hudson B.G. (2008) “A role for collagen IV crosslinks in conferring immune privilege to the Goodpasture autoantigen: Structural basis for the crypticity of B cell epitopes” J Biol Chem. 283(33):22737-22748.  Download PDF pdf-icon-transparent.gif

Vanacore, R.M., Friedman, D.B., Ham, A.J., Sundaramoorthy, M., Hudson, B.G. (2005). “Identification of S-hydroxylysyl-methionine as the covalent cross-link of the noncollagenous (NC1) hexamer of the α1α1α2 collagen IV network: a role for the post-translational modification of lysine–211 to hydroxylysine–211 in hexamer assembly”. J Biol Chem. 280:29300-10.   Download PDF pdf-icon-transparent.gif

Vanacore, R.M., Shanmugasundararaj, S, Friedman, DB, Bondar, O, Hudson, BG, Sundaramoorthy, M. (2004). “The α1α1α2 network of collagen IV. Reinforced stabilization of the Noncollagenous Domain-1 by Noncovalent Forces and the Absence of Met-Lys Crosslinks”. J Biol Chem. 279:44723-30.   Download PDF pdf-icon-transparent.gif

Vanacore, RM., Eskew, J.D., Morales, P.J., Sung L. and Smith, A. (2000) “Role for Copper in Transient Oxidation and Nuclear Translocation of MTF-1, But Not of NF-KB, by The Heme-Hemopexin Transport System” Antioxidants & Redox Signaling, 2: 739-752.  Download PDF pdf-icon-transparent.gif

*Eskew, J.D., *Vanacore, RM., Morales, P.J., Sung, L. and Smith, A. (1999) “Cellular Protection Mechanism Against Extracellular Heme:  Heme-Hemopexin But Not Free Heme, Activates The MAP Kinase Family Member N-Terminal c-Jun Kinase”. J Biol Chem, 274: 638‑648. *Authors contributed equally to the research.  Download PDF pdf-icon-transparent.gif

Villanueva, J., Vanacore, RM., Goicoechea, O. and Amthauer, R. (1997) “Intestinal Alkaline  Phosphatase of the Fish Cyprinus carpio: Regional Distribution and Membrane Association”. J Exp Zool, 279: 347-355.  Download PDF pdf-icon-transparent.gif