Clinical Practice Guidelines: Urinary Tract Infection



Urinary tract infection (UTI) is the second most common serious bacterial infection in children, accounting for 500,000 pediatric emergency department visits and more than 1 million clinic visits annually in the United States. Costs for management and treatment add up to approximately $600 million per year.

This clinical practice guideline was developed with the goal of standardization of treatment for acute urinary tract infection, based on current evidence and best practices. The most common pathogen causing urinary tract infection is E. coli, and local rates of first-generation cephalosporin susceptibility are comparable to broader spectrum antibiotics. Therefore, the clinical practice guideline focuses on providing high-quality, cost-effective care by using empiric narrow spectrum antibiotics, following urine culture results, and altering antibiotic therapy accordingly.

Urinary tract infection guideline team

  • Contact: Sophie Katz, Infectious Diseases
  • Donald Arnold, M.D., MPH, Emergency Medicine
  • Kathryn Carlson, M.D., MMHC, General Pediatrics
  • Kevin Glatt, M.D., General Pediatrics
  • Alison Herndon, M.D., MSPH, Hospital Medicine
  • John Thomas, M.D., Urology
  • Rene Vandevoorde, M.D., Nephrology