Lindman BR, Breyley JG, Schilling JD, Vatterott AM, Zajarias A, Maniar HS, Damiano RJ, Moon MR, Lawton JS, Gage BF, Sintek MA, Aquino A, Holley CL, Patel NM, Lawler C, Lasala JM, Novak E. Prognostic utility of novel biomarkers of cardiovascular stress in patients with aortic stenosis undergoing valve replacement. Heart (British Cardiac Society). 2015 Sep;101(101). 1382-8. PMID: 26037104 [PubMed] PMCID: PMC4598053 NIHMSID: NIHMS725964.
In heart failure populations without aortic stenosis (AS), the prognostic utility of multiple biomarkers in addition to clinical factors has been demonstrated. We aimed to determine whether multiple biomarkers of cardiovascular stress are associated with mortality in patients with AS undergoing aortic valve replacement (AVR) independent of clinical factors.