Brittain EL, Doss LN, Saliba L, Irani W, Byrd BF, Monahan K. Feasibility and Diagnostic Potential of Pulmonary Transit Time Measurement by Contrast Echocardiography: A Pilot Study. Echocardiography (Mount Kisco, N.Y.). 2015 Oct;32(32). 1564-71. PMID: 25682691 [PubMed] PMCID: PMC4536186 NIHMSID: NIHMS655364.
Pulmonary transit time (PTT; the time for ultrasound contrast to travel from the right ventricle [RV] to the left atrium) may provide a single metric that reports on cardiopulmonary function while overcoming some of the challenges of standard echocardiographic measures. We conducted a pilot study to test the feasibility and reproducibility of echocardiographically derived PTT and to determine its association with established measures of cardiopulmonary function.