Chacha F, Mirambo MM, Mushi MF, Kayange N, Zuechner A, Kidenya BR, Mshana SE. Utility of qualitative C- reactive protein assay and white blood cells counts in the diagnosis of neonatal septicaemia at Bugando Medical Centre, Tanzania. BMC pediatrics. 2014 Oct 3;14(14). 248 p. PMID: 25280754 [PubMed] PMCID: PMC4192733
Neonatal septicaemia diagnosis based on clinical features alone is non-specific leading to the initiation of unnecessary antibiotic treatment posing a danger of increased antibiotic resistance. In the present study the utility of serial qualitative C-reactive protein (CRP) assay and white blood cells count (WBC) in the diagnosis of neonatal septicaemia was investigated using blood culture as gold standard.