Effects of polymorphisms in translesion DNA synthesis genes on lung cancer risk and prognosis in Chinese men.

Xu HL, Gao XR, Zhang W, Cheng JR, Tan YT, Zheng W, Shu XO, Xiang YB. Effects of polymorphisms in translesion DNA synthesis genes on lung cancer risk and prognosis in Chinese men. Cancer epidemiology. 2013 Dec;37(37). 917-22. PMID: 24012694 [PubMed] PMCID: PMC3875838 NIHMSID: NIHMS515182.

Abstract

Translesion DNA synthesis (TLS) plays an important role in promoting replication through DNA lesions. Genetic polymorphisms in TLS genes may have potential roles in lung cancer development in humans.