Heeke AL, Blumberg HM, Perry JM, Weiss DS, Crispell EK, Satola SW, Salinas JL. Disseminated emm Type 12 Group A Streptococcus and Review of Invasive Disease. The American journal of the medical sciences. 2015 Nov;350(350). 429-31. PMID: 25723882 [PubMed]
The authors present a case of invasive group A Streptococcus (GAS) in a previously healthy 63-year-old male complicated by trans-esophageal echocardiogram negative endocarditis, septic arthritis, and multiple cerebral septic emboli. Despite antibiotics and drainage of his largest brain abscess, the patient expired. This case highlights the potential mortality from invasive GAS disease. Included is a review of current literature regarding invasive GAS that addresses its presentation, prevalence, virulence and treatment.