Ramirez AG, Shada AL, Martin AN, Raghavan P, Durst CR, Mukherjee S, Gaughen JR, Ornan DA, Hanks JB, Smith PW. Clinical efficacy of 2-phase versus 4-phase computed tomography for localization in primary hyperparathyroidism. Surgery. 2016 Dec;160(160). 731-7. PMID: 27302106 [PubMed] PMCID: PMC4975639 NIHMSID: NIHMS803430.
Four-dimensional computed tomography is being used increasingly for localization of abnormal glands in primary hyperparathyroidism. We hypothesized that compared with traditional 4-phase imaging, 2-phase imaging would halve the radiation dose without compromising parathyroid localization and clinical outcomes.