The U.S. Preventive Services Task Force (USPSTF) has formally recommended changes to lung cancer screening guidelines in an effort to reduce outcome disparities between African American and white patients.
The decision is based in part on research led by Melinda Aldrich, Ph.D., an associate professor of medicine at Vanderbilt University Medical Center. The research team included Kim Sandler, M.D., an assistant professor of radiology and radiological sciences and co-director of the Vanderbilt Lung Screening Program.
TREAT team member research published in JAMA Oncology has played a key role in new lung cancer screening guidelines. VUMC Reporter article "Vanderbilt research played key role in new lung screen guidelines" highlights the effect this research, whose authors include TREAT members Melinda Aldrich, PhD, MPH, Kim Sandler, MD, Eric Grogan, MD, MPH, and Jeffrey Blume, PhD, had on new USPSTF lung cancer screening guidelines.
A team of investigators, including TREAT members Eric Grogan, MD, MPH, Stephen Deppen, PhD, and Maren Shipe, MD, MPH, created complex decision analysis models that balanced the risk of COVID-19 infection against the risk of disease progression if surgical procedures were delayed during the pandemic. When the team analyzed six specific disease-surgery pairs in relation to model patients, they determined that proceeding with surgery in hospitals with low perioperative COVID-19 infection rates rather than waiting three to six months would likely result in an improved five-year survival for the patients.
Examining CT scans for smokers
The U.S. Preventive Services Task Force (USPSTF) guidelines that determine which smokers qualify for CT scans exclude significant numbers of African Americans who develop lung cancer, a health disparity that merits modifications to lung cancer screening criteria, according to a study from Vanderbilt researchers. The researchers concluded that those guidelines may be too conservative for African Americans, setting the stage for later diagnoses and reduced odds of survival.
The U.S. Preventive Services Task Force (USPSTF) guidelines that determine which smokers qualify for CT scans exclude significant numbers of African Americans who develop lung cancer, a health disparity that merits modifications to lung cancer screening criteria, according to a study from Vanderbilt researchers, and TREAT members, Melinda Aldrich, PhD, MPH, Kim Sandler, MD, Eric Grogan, MD, MPH, and Jeffrey Blume, PhD, as well as William Blot, PhD, and Sarah Mercaldo, PhD.
TREAT members Eric Grogan, MD, MPH, and Stephen Deppen, PhD, are featured in this Discover article highlighting their research in distinguishing cancer from fungal infection. The Discover series spotlights breakthroughs in medical science and patient care from Vanderbilt University Medical Center.
The Vanderbilt team studying histoplasmosis includes TREAT team members (front row, from left) Heidi Chen, PhD, Melinda Aldrich, PhD, MPH, (back row, from left) Stephen Deppen, PhD, Eric Grogan, MD, MPH, and Jeffrey Blume, PhD. (photo by Steve Green).
Their work, published October 2018 in Emerging Infectious Diseases, revealed that histoplasmosis is prevalent beyond previously identified regions of the United States and led to the U.S. Centers for Disease Control and Prevention (CDC) updating its maps in December.
An illness and CT-scan led to a diagnosis of lung cancer for Mr. Taylor Stokes. TREAT member Eric Grogan, MD, MPH, performed the surgery to remove the tumor from Mr. Stokes’ lung and now Mr. Stokes has annual follow-up scans through Vanderbilt’s Lung Screening Program. Read Mr. Stokes’ story at www.mysouthernhealth.com.
Vanderbilt University Medical Center’s (VUMC) Lung Screening Program for patients at high risk for cancer recently reached a milestone, enrolling more than 700 patients and performing more than 1,000 CT screening examinations. TREAT member Kim Sandler, MD, Assistant Professor of Radiology and Radiological Sciences, is co-director of the Lung Screening Program.
Dr. Eric Grogan appears on NewsChannel 5 OpenLine along with Dr. Pierre Massion, Director of the Vanderbilt-Ingram Cancer Center (VICC) Cancer Early Detection and Prevention Initiative, and lung cancer survivor Kathy Leiser. The segment promotes lung cancer awareness and highlights developments in the treatment of lung cancer.
Members of the TREAT team will participate in a recently awarded U54 grant which will build a Vanderbilt-Meharry-Miami Center of Excellence for Precision Medicine and Population Health. The new center will enable research using approaches to precision medicine to eradicate health disparities, specifically those among African Americans and Latinos.
Melinda Aldrich, Ph.D., is interviewed on Lehman College's Public Health Minute with William Latimer regarding her research focusing on lung cancer in African Americans.