Mark Does, Ph.D.

Mark Does, Ph.D.

Professor of Biomedical Engineering

5822 Stevenson Center Nashville TN 37235
(615) 322-8352 (office)

Research Description

Mark Does, Ph.D., received a bachelor of science and a master of science in electrical engineering, and a doctorate in biomedical engineering from the University of Alberta. He joined the Vanderbilt faculty in 2002 as part of the establishment of the Institute of Imaging Sciences. He is Professor of Biomedical Engineering, Electrical Engineering, and Radiology and Radiological Sciences, and he serves as the Director of the Center for Small Animal Imaging. In 2014, Dr. Does was elected into the American Institute for Medical and Biological Engineering’s (AIMBE) College of Fellows.

The Does lab is motivated by development, evaluation, and application of magnetic resonance imaging (MRI) methods for characterizing tissue microstructure, composition, and function. To this end, we develop novel MRI pulse sequences and analysis methods; evaluate and apply methods in studies of humans and small animal models of disease/injury/abnormal development; and develop and utilize statistical methods and computational models to predict and explain MRI contrast in tissues.

Current Research Projects:

-Characterization of Neural Tissue and Skeletal Muscle with MRI
using Relaxation, Magnetization Transfer, and Diffusion

-Compartmental Modelling of Water Proton Relaxation and Diffusion
with computational methods, chemical phantoms, and compartment-specific contrast agents

-Cortical Bone Imaging with Magnetic Resonance

-Development/Optimization of MRI pulse sequence
for rapid relaxometry
for diffusion measurement at very short diffusion times
for small animal cardiac imaging,
for MR microscopy

Selected Publications