Young Jun Kim, Ph.D., M.D.

Professor of Otolaryngology
Barry and Amy Baker Chair in Laryngeal, Head and Neck Research
Professor of Pathology, Microbiology and Immunology

602 Oxford House
1313 21st Avenue South
Nashville
Tennessee
37232-4480
(615) 936-5000

Head & neck surgery, squamous cell carcinoma, otolaryngology

Research Description

The Kim laboratory is focused on the Immunological components of the tumor microenvironment under the context of translating the findings towards clinical trials. We have characterized the adaptive immune resistance mechanisms of PD-L1 on the tumor cells that have resulted in a clinical impetus towards combination of cancer vaccines, adjuvants, radiation, and/or targeted oncological agents with immune checkpoint inhibitors. We are  focused on the STING pathway, neoantigen development, as well as other targetable immune checkpoint inhibitors and co-activators such as NKG2A, NKG2D, KIRs, TIGIT.

Publications on PubMed.gov