Kevin G. Osteen, PhD

Professor
Obstetrics and Gynecology
Professor
Pathology, Microbiology, and Immunology
Pierre Soupart Chair
Obstetrics and Gynecology

Division: Research
Research Interests: Endometriosis, Environmental Toxins, Dioxin, Reproduction and Toxin Exposure

Kevin G. Osteen, Professor of Professor of Obstetrics and Gynecology, Professor of Pathology, Microbiology and Immunology at Vanderbilt University School of Medicine and is an Adjunct Professor of Obstetrics and Gynecology at Meharry Medical College.  He currently holds the Pierre Soupart Chair in Obstetrics and Gynecology.  Dr. Osteen also directs the International Endometriosis Association Research Program at Vanderbilt and has served as an advisor to various biotechnology and large pharmaceutical companies.

Dr. Osteen received his B.S. degree from the University of South Carolina and his Ph. D. degree from the Medical College of Georgia in 1980. He completed his postdoctoral training in reproductive physiology at the University of Maryland School of Medicine in Baltimore, MD under the mentorship of Dr. Cornelia Channing.

Dr. Osteen moved to Vanderbilt University School of Medicine as an Instructor of Obstetrics and Gynecology in 1983 as a member of the team that launched the first in vitro fertilization (IVF) program in Tennessee and the fourth program in the United States. He also helped establish a board-certification program for basic scientists who desired to become directors of IVF programs. Having trained in basic and translational endocrinology, Dr. Osteen’s research program has always focused on the clinical relevance of his basic science initiatives. Since the 1990s his research program has focused on the relevance of environmental endocrine disruptors in the pathophysiology of infertility related to the disease endometriosis.  In particular, his laboratory has focused on the potential that early life exposure to environmental toxicants may set the stage for adult onset diseases affecting reproductive success by disrupting normal steroid-mediated cell-cell communication.  Recent research efforts in his laboratory have begun to use recently developed “organ-on-a-chip” technology to create the first endometrium and endometriosis chip models. These models will provide a comparative system in which to investigate the intrinsic properties and hyper-inflammatory state of a normal and endometriosis endometrium that promotes disease progression.