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Thompson MG, Sokolow LZ, Almendares O, Openo K, Farley MM, Meek J, Ray J, Kirley PD, Reingold A, Aragon D, Hancock E, Baumbach J, Schaffner W, Thomas A, Lynfield R, Ryan P, Monroe M, Cheng PY, Fry AM, Shay DK. Effectiveness of nonadjuvanted monovalent influenza A(H1N1)pdm09 vaccines for preventing reverse transcription polymerase chain reaction-confirmed pandemic influenza hospitalizations: case-control study of children and adults at 10 US influenza surveillance network sites. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2013 Dec;57(57). 1587-92.
Abstract
During 2009-2010, we examined 217 patients hospitalized with laboratory-confirmed pandemic influenza in 9 Influenza Hospitalization Surveillance Network sites and 413 age- and community-matched controls and found that a single dose of monovalent nonadjuvanted influenza A(H1N1)pdm09 vaccine was 50% (95% confidence interval, 13%-71%) effective in preventing hospitalization associated with A(H1N1)pdm09 virus infection.